Mouse anti Human p21 Antibody, Recombinant (MyM1-p21), could be used for IHC and so on. Application IHC: 1/100-1/200 Protein Function May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
Recombinant p21 Antibody (Ab119617) - IHC Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue labelling p21 with Recombinant p21 Antibody (Ab119617) at 1/100 dilution. The section was incubated with Ab119617 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.
Recombinant p21 Antibody (Ab119617) - IHC Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue labelling p21 with Recombinant p21 Antibody (Ab119617) at 1/100 dilution. The section was incubated with Ab119617 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.