The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
宿主种属
小鼠(Mouse)
特异性
Phospholipase C beta 1/PLCB1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
Recombinant protein of human PLCB1 (AA 31-240)
阳性对照
WB: Rat brain and Mouse brain lysates.
偶联
Unconjugated
克隆类型
单克隆抗体
Format
Whole IgG
亚型
Rabbit IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
1.0 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
150mM PBS, 0.09% Sodium azide, pH 7.4.
防腐剂
0.09% Sodium azide
储存条件
-80℃储存,避免反复冻融
运输条件
特低温运输
稳定性与储存
4℃ 短期储存（1-2 周）。-20℃长期保存（24 个月）。收货后建议分装。避免冷冻/解冻循环。
图片
Phospholipase C beta 1/PLCB1 Mouse mAb (Ab121657) - Western Blot All lanes: Phospholipase C beta 1/PLCB1 Mouse mAb (Ab121657) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/10000 dilution
Predicted band size: 139 kDa Observed band size: 100, 150 kDa The study reveals that calpain cleaves PLC-beta 1 at the junction of residues 880 and 881, producing 100 kDa and 45 kDa proteins, with the region between residue 881 and the carboxyl-terminal 10 kDa being essential for G alpha q interaction, while a 140 kDa protein, activated by G alpha q, is not derived from PLC-beta 1.(PMID: 8429045). Exposure time: 56.3 s
ZJ25F0116612
危险品化学品经营许可证（带存储）