Rab-11 | YL8 | MGC1490 antibody | Rab 11 antibody | Rab 11A antibody | RAB 11A, member oncogene family antibody | Rab-11 antibody | RAB11 A antibody | RAB11 antibody | Rab11a antibody | RAB11A member RAS oncogene family antibody | Ras related protein Rab
规格或纯度
ExactAb™, Validated, Carrier Free, High performance, 0.5 mg/mL
生化机理
Regulates endocytic recycling. May exert its functions by interacting with multiple effector proteins in different complexes. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity). Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes.
宿主种属
小鼠(Mouse)
特异性
Rab11A
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
Recombinant protein of human RAB11A (AA 1-216)
阳性对照
WB: HeLa, Jurkat, HEK293, A549, MCF7, NIH/3T3 and C6 cell lysates. IHC: Human brain tissue.
偶联
Unconjugated
克隆类型
单克隆抗体
克隆号
1565CT164.36.80
Format
Whole IgG
亚型
Mouse IgG1
轻链亚型
kappa
纯化方法
Protein G purified
浓度
0.5 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBS, 0.09% Sodium azide, pH 7.4
防腐剂
0.09% Sodium azide
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。
图片
Rab11A Mouse mAb (Ab124104) - Western Blot All lanes: Rab11A Mouse mAb (Ab124104) at 1/4000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 24 kDa Observed band size: 24 kDa Exposure time: 22.1 s
Rab11A Mouse mAb (Ab124104) - IHC Rab11A Mouse mAb (Ab124104) staining RAB11A in human brain sections by Immunohistochemistry. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH 6.0). Samples were incubated with Rab11A Mouse mAb (Ab124104) (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
ZJ24F0303554
危险品化学品经营许可证（带存储）