ExactAb™,已验证,无载体,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Mouse anti Human Transferrin Receptor Antibody, Recombinant (10F11), could be used for IHC and so on.
Application
Protein Function
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. Positively regulates T and B cell proliferation through iron uptake (PubMed:26642240).
(Microbial infection) Acts as a receptor for new-world arenaviruses: Guanarito, Junin and Machupo virus.
Recombinant Transferrin Receptor Antibody (Ab132243) - IHC
Immunohistochemistry analysis of paraffin-embedded human placenta tissue labelling Transferrin Receptor with Recombinant Transferrin Receptor Antibody (Ab132243) at 1/50 dilution. The section was incubated with Ab132243 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.
1/50-1/100
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0505384 |
分析证书 | Ab132243 |
| ZJ24F0505385 |
分析证书 | Ab132243 |
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