Farletuzumab (anti-FOLR1), 叶酸受体 alpha 抑制剂

    应用:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
功能和特点
  • 宿主种属: 人(Human)
  • 种属反应性: 人(Human)
  • 亚型: Human IgG1
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab170540-100μg
100μg 期货 Stock Image
Ab170540-1mg
1mg 现货 Stock Image
Ab170540-5mg
5mg 现货 Stock Image
Ab170540-10mg
10mg 现货 Stock Image

基本信息

产品名称 Farletuzumab (anti-FOLR1), 叶酸受体 alpha 抑制剂
别名 法瑞珠单抗(抗 FOLR1)
英文别名 Adult folate-binding protein | FBP | Folate receptor 1 | Folate receptor, adult | FR-alpha | KB cells FBP | Ovarian tumor-associated antigen MOv18
规格或纯度 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属 人(Human)
特异性 FOLR1
种属反应性 人(Human)
偶联 Unconjugated
作用类型 抑制剂
作用机制 叶酸受体 alpha 抑制剂

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Human IgG1
轻链亚型 kappa
SDS-PAGE 26.9 kDa (Light Chain) & 52.2 kDa (Heavy Chain), under reducing conditions; 181.9 kDa, under non-reducing conditions.
纯化方法 Protein A purified
纯度 >95%
物理外观 Liquid
储存缓冲液 Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂 No
浓度 见COA
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息 896723-44-7
分子类型 抗体

图片

Farletuzumab (anti-FOLR1) (Ab170540) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling FOLR1 (red) with Farletuzumab (anti-FOLR1) (Ab170540). Goat Anti-Human IgG (FITC) (Ab175834) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Farletuzumab (anti-FOLR1) (Ab170540) - SEC
The purity of Farletuzumab (anti-FOLR1) (Ab170540) is more than 95% verified by HPLC.

Farletuzumab (anti-FOLR1) (Ab170540) - ELISA
Immobilized huFOLR1 at 2 μg/mL can bind Farletuzumab (anti-FOLR1) (Ab170540) with the EC₅₀ of 18.95 ng/mL.

关联靶点(人)

FOLR1 Tclin 叶酸受体α(Folate receptor alpha) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

安全和危险性(GHS)

技术规格说明书

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ23F0800915 分析证书 25-05-23 Ab170540
ZJ23F0800916 分析证书 25-05-23 Ab170540
ZJ23F0800917 分析证书 25-05-23 Ab170540

参考文献

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