药物发现
选项
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Recombinant Mouse FGF-21 Protein
- 种属: 小鼠(Mouse)
- Accession #: Q9JJN1
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <0.1 EU/μg
- 生物活性: Fully biologically active when compared to standard. The ED₅₀ as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/ml, corresponding to a specific activity of >2.0 ×10³IU/mg in the presence of 5 µg/ml of rMuβ-Klotho and 10 μg/ml of heparin.
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Recombinant Mouse IL-10 Protein
- 种属: 小鼠(Mouse)
- Accession #: P18893
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured in a cell proliferation assay using MC/9‑2 mouse mast cells. The ED₅₀ for this effect is 0.8 ng/mL.
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Recombinant Mouse Sonic Hedgehog/Shh Protein
- 种属: 小鼠(Mouse)
- Accession #: Q62226
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to induce alkaline phosphatase production by C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is 0.6-3 µg/mL.
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Recombinant Mouse TSLP Protein
- 种属: 小鼠(Mouse)
- Accession #: Q9JIE6
- 表达系统: HEK293
- 蛋白标签: C-10His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured in a cell proliferation assay using BaF3 mouse pro‑B cells transfected with mouse IL-7 R alpha. The ED50for this effect is 0.5-2.5 ng/mL.
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Recombinant Mouse PD-L1/B7-H1 Protein
- 种属: 小鼠(Mouse)
- Accession #: Q9EP73
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Immobilized Recombinant Mouse PD-L1/B7-H1 Protein (rp154493) at 10 μg/mL can bind Recombinant Mouse PD-1 Protein (rp149974), the EC₅₀ of this effect is 3.07 μg/mL.
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Recombinant Mouse IL-22 Protein
- 种属: 小鼠(Mouse)
- Accession #: Q9JJY9
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to induce IL-10 secretion in COLO 205 human colorectal adenocarcinoma cells. The ED50 for this effect is 60-300 pg/mL.
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Recombinant Mouse TNF-alpha Protein
- 种属: 小鼠(Mouse)
- Accession #: P06804
- 表达系统: HEK293
- 蛋白标签: No tag
- 内毒素水平: <0.1 EU/μg
- 生物活性: Recombinant Mouse TNF-alpha induces cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 29-116 pg/mL, corresponding to a specific activity of 8.62×10^6-3.45×10^7 units/mg.
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Recombinant Mouse VEGF 164 Protein
- 种属: 小鼠(Mouse)
- Accession #: Q00731-2
- 表达系统: HEK293
- 蛋白标签: N-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 0.8-4 ng/mL.
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Recombinant Mouse TGF-beta 1 Protein
- 种属: 小鼠(Mouse)
- Accession #: P04202
- 表达系统: HEK293
- 蛋白标签: N-8His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Recombinant Mouse TGF-beta 1 inhibits the IL-4-dependent proliferation of HT-2 mouse T cells. The ED50 for this effect is 0.02-0.1 ng/ml.
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Recombinant Mouse IL-23 Protein
- 种属: 小鼠(Mouse)
- Accession #: P43432,Q9EQ14
- 表达系统: HEK293
- 蛋白标签: C-His (IL-23a) & No tag (IL-12b)
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to induce IL-17 secretion by mouse splenocytes.The ED50 for this effect is 0.05-0.25 ng/mL.
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Recombinant Mouse IL-17A Protein
- 种属: 小鼠(Mouse)
- Accession #: Q62386
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Immobilized Recombinant Mouse IL-17A Protein (rp154149) at 2.0 μg/mL can bind Mouse IL- 17RA/CD217 with the EC50 for this effect is 16.01ng/mL.
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Recombinant Mouse IL-6 Protein
- 种属: 小鼠(Mouse)
- Accession #: P08505
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured in a cell proliferation assay using NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.07-0.28 ng/mL, corresponding to a specific activity of 3.57×10^6 ~ 1.43×10^7 units/mg.