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药物发现
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Recombinant Human ErbB2/Her2 Protein
- 种属: 人(Human)
- Accession #: P04626
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Immobilized recombinant human ERBB2 at 10 ng/mL (100 μL/well) can bind Trastuzumab with a linear range of 4-20 ng/mL.
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Recombinant Human FGFR1 Protein
- 种属: 人(Human)
- Accession #: P11362
- 表达系统: HEK293
- 蛋白标签: C-hFc & His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to inhibit FGF1 dependent proliferation of Balb/c-3T3 cells. The ED50 for this effect is typically 0.5-5 ng/mL.
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Recombinant Human FGFR4 protein
- 种属: 人(Human)
- Accession #: P22455
- 表达系统: HEK293
- 蛋白标签: C-hFc & His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.03-0.12 ng/mL.
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Recombinant Human IL-17RA/IL-17R Protein
- 种属: 人(Human)
- Accession #: Q96F46
- 表达系统: HEK293
- 蛋白标签: C-hFc & His
- 内毒素水平: <0.01 EU/μg
- 生物活性: Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.03‑0.1 µg/mL in the presence of 10 ng/mL recombinant human IL‑17.
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Recombinant Human IL1 Receptor I/IL-1R-1 Protein
- 种属: 人(Human)
- Accession #: P14778
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to inhibit proliferation using D10.G4.1 mouse helper T cells. The ED50 for this effect is 0.2-1.0 µg/mL with human IL-1 beta.
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Recombinant Human PD-L2/B7-DC Protein
- 种属: 人(Human)
- Accession #: Q9BQ51
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.01 EU/μg
- 生物活性: Immobilized Recombinant Human PD-L2 at 5 μg/mL (100 μL/well) can bind Recombinant Human PD-1 with a linear range of 0.2-1.0 μg/mL.
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Recombinant Human TIM 3 Protein
- 种属: 人(Human)
- Accession #: Q8TDQ0
- 表达系统: HEK293
- 蛋白标签: C-hFc & His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Immobilized Human Galectin-9 at 2 μg/mL can bind recombinant human TIM-3 with a linear range of 0.3 - 5 μg/mL.
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Recombinant Human TIGIT Protein
- 种属: 人(Human)
- Accession #: Q495A1
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Immobilized Human TIGIT at 1.5 μg/mL (100 μL/well) can bind Human CD155 with a linear range of 0.15-1.2 μg/mL.
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Recombinant Human gp130 Protein
- 种属: 人(Human)
- Accession #: P40189
- 表达系统: HEK293
- 蛋白标签: C-hFc & His
- 内毒素水平: <0.01 EU/μg
- 生物活性: Measured by its ability to inhibit IL-6-dependent proliferation of the 7TD1 mouse hybridoma cells in the presence of Recombinant Human IL-6 R alpha.The ED₅₀ for this effect is 0.65-6.5 ng/mL.
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Recombinant Human CD33 Protein
- 种属: 人(Human)
- Accession #: P20138
- 表达系统: HEK293
- 蛋白标签: C-hFc & His
- 内毒素水平: <0.1 EU/μg
- 生物活性: 1、Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. The ED50 for this effect is 1‑4 µg/mL. 2、Immobilized Recombinant Human CD33 Protein (rp143966) at 2.0 μg/mL can bind Gemtuzumab (anti-CD33) (Ab175859). The ED50 for this effect is 391.3 ng/mL.
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Recombinant Human CD276 Protein
- 种属: 人(Human)
- Accession #: Q5ZPR3-2
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: 1、Immobilized Recombinant Human CD276 Protein (rp143912) at 0.5 μg/mL can bind Anti Human CD276 Antibody with the EC50 of 10.73 ng/mL. 2、Immobilized Recombinant Human CD276 Protein (rp143912) at 1 μg/mL can bind Anti Human CD276 Antibody with a linear range of 1 - 4 ng/mL (EC50:4.3 ng/mL).
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Recombinant Human CD277/BTN3A1 Protein
- 种属: 人(Human)
- Accession #: O00481
- 表达系统: HEK293
- 蛋白标签: C-hFc & His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured by its ability to inhibit Anti-CD3-induced proliferation of jurkat. The ED₅₀ for this effect is 20-100 ng/mL.
