药物发现
选项
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Recombinant Human G-CSF Protein
- 种属: 人(Human)
- Accession #: P09919-2
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <0.1 EU/μg
- 生物活性: Measured in a cell proliferation assay using NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 1.05 pg/mL.
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Recombinant Mouse TNF-alpha Protein
- 种属: 小鼠(Mouse)
- Accession #: P06804
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <0.01 EU/μg
- 生物活性: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.1 ng/mL.
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Recombinant Human BAFFR/TNFRSF13C Protein
- 种属: 人(Human)
- Accession #: Q96RJ3
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <1.0 EU/μg
- 生物活性: Fully biologically active when compared to standard. The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0 μg/ml in the presence of 1.0 μg/ml of rHuBAFF.
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Recombinant Human 4-1BB Ligand Protein
- 种属: 人(Human)
- Accession #: P41273
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <1.0 EU/μg
- 生物活性: Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml.
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Recombinant Human Osteoprotegerin Protein
- 种属: 人(Human)
- Accession #: O00300
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <1.0 EU/μg
- 生物活性: Fully biologically active when compared to standard. The ED50 as determined by neutralizing the stimulation of U937 cells is less than 10 ng/ml in the presence of 10 ng/mL soluble rHuRANKL (sRANKL).
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Recombinant Human TNFRSF1A Protein
- 种属: 人(Human)
- Accession #: P19438
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <0.1 EU/μg
- 生物活性: Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha.
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Recombinant Human Leptin Protein
- 种属: 人(Human)
- Accession #: P41159
- 表达系统: E. coli
- 蛋白标签: No tag
- 内毒素水平: <1.0 EU/μg
- 生物活性: Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human Leptin R transfected BaF3 murine proB cells is less than 2 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg.
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Recombinant Human TNF RII/TNFRSF1B Protein
- 种属: 人(Human)
- Accession #: P20333
- 表达系统: E. coli
- 蛋白标签: N-His & GST
- 内毒素水平: <1.0 EU/mg
- 生物活性: The binding activity of TNFRSF1B and TNFa, the EC50 was 0.0470~0.085 μg/ml.
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Recombinant Human CD80 Protein
- 种属: 人(Human)
- Accession #: P33681
- 表达系统: HEK293
- 蛋白标签: N-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Measured by its binding activity of recombinant human CD80 and recombinant human CD86. The EC50 for this effect is less than 0.412μg/mL.
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Recombinant Human IL-2 Receptor Alpha Protein
- 种属: 人(Human)
- Accession #: P01589
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: 1. Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.2 ‑1.2 µg/mL in the presence of 30 ng/mL of recombinant human IL-2. 2. Immobilized Recombinant Human IL-2 Protein (rp156004) at 1 μg/mL can bind biotinylated Recombinant Human IL-2 Receptor Alpha Protein (rp147480).
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Recombinant Human Nectin-3 Protein
- 种属: 人(Human)
- Accession #: Q9NQS3
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: Recombinant Human Nectin-3 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human PVRL1/NECTIN1 hFc has been identified as an interactor of Nectin-3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-3 and recombinant PVRL1/NECTIN1 hFc.
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Recombinant Human IL-6R Protein
- 种属: 人(Human)
- Accession #: P08887
- 表达系统: HEK293
- 蛋白标签: C-His
- 内毒素水平: <1.0 EU/μg
- 生物活性: 1. Immobilized Recombinant Human IL-6 Protein at 2 μg/mL can bind Recombinant Human IL-6R Protein (rp147628) the EC50 is 8.0 - 24.0 ng/mL. 2. Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10.0 - 60.0 ng/mL.3. Using the Octet RED System, the affinity constant (Kd) of Recombinant Human IL-6R Protein (rp147628) bound Anti-IL6R Antibody was 0.1 nM.