概述规格名称和识别符技术文档高级数据系统学分类三维结构质检证书（CoA,COO,BSE/TSE 和分析图谱) 化学和物理性质安全和危险性（GHS）此产品的引用文献技术文档和文章引用文献溶液计算器

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为什么选择此级别

提供 ≥98% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

-20°C储存,充氩。超低温运输。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 211 篇同行评审文献引用。

概述

用于N-基团保护的氨基酸和其它酸的N-琥珀酰亚胺酯制备的常用试剂；用于激活的碳酸盐，如合成尿素。

Product Application

N,N′-Disuccinimidyl carbonate may be used: As an activating reagent for the reactive patterning of polymer brushes to couple primary amines via post-functionalization. As an alkoxycarbonylating reagent for a variety of primary and sterically hindered secondary alcohols, which further allows the synthesis of different structurally diverse carbamates. As a coupling agent for the synthesis of thiophospholipids, commonly used for anchoring biomembranes to gold surfaces. It can also be used to prepare a heterobifunctional, cleavable linker-SVEC-(succinimide vinylsufonylethyl carbonate)-for thiol modified-DNA.

规格

别名

英文别名

BCP29435 | di (n-succinimidyl) carbonate | 2,5-dioxoazolidinyl (2,5-dioxoazolidinyloxy)formate | C93507 | Bis(2,5-dioxopyrrolidin-1-yl) carbonate;Di(succinimido) carbonate | N,N'-Disuccinimidyl carbonate, Tech Grade | Q-201437 | C9H8N2O7 | EC 277-730-3 |

规格或纯度

≥98%

英文名称

N.N'-Disuccinimidyl Carbonat (DSC)

储存条件

-20°C储存,充氩

运输条件

超低温运输

纯度

≥98%

名称和识别符

PubChem SID

528765691

EC号

277-730-3

分子类型

小分子

IUPAC Name

bis(2,5-dioxopyrrolidin-1-yl) carbonate

INCHI

1S/C9H8N2O7/c12-5-1-2-6(13)10(5)17-9(16)18-11-7(14)3-4-8(11)15/h1-4H2

InChi Key

PFYXSUNOLOJMDX-UHFFFAOYSA-N

Smiles

C1CC(=O)N(C1=O)OC(=O)ON2C(=O)CCC2=O

Isomeric SMILES

C1CC(=O)N(C1=O)OC(=O)ON2C(=O)CCC2=O

分子量

256.17

Beilstein号

1499137

Reaxy-Rn

1499137

Reaxys-RN link address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1499137&ln=

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

查询 COA →

📊 产品数据表

产品规格和应用的快速参考摘要。

查看数据表 →

🔬 规格说明书

该级别的完整质量属性和验收标准。

查看规格说明 →

高级数据

系统学分类

分类树（Taxonomy Tree）

界（kingdom) 有机化合物
- 超类（Superclass) 有机杂环化合物
  - 类（Class) 吡咯烷
    - 亚类（Subclass）吡咯烷酮

界（kingdom)	有机化合物
超类（Superclass)	有机杂环化合物
类（Class)	吡咯烷
亚类（Subclass）	吡咯烷酮
中间层级节点（Intermediate Tree Nodes）	暂无
直接上位类(Direct Parent)	吡咯烷-2-酮
其他上位类（Alternative Parents）	二羧酰亚胺有机碳酸及其衍生物内酰胺类氮杂环化合物有机光子化合物有机氮化合物有机氧化物碳氢化合物衍生物羰基化合物
分子骨架（Molecular Framework)	脂肪族杂单环化合物
取代基（Substituents）	2-吡咯烷酮 - 脂肪族杂单环化合物 - 氮杂环 - 碳酸衍生物 - 羰基 - 羧酸衍生物 - 二羧酰亚胺 - 烃衍生物 - 肟 - 有机硝基化合物 - 有机氧化物 - 有机氧化合物 - 有机氮化合物 - 有机氧化合物 - 有机氮化合物
描述（Description）	该化合物属于吡咯烷-2-酮类有机化合物。这类化合物在吡咯烷环2位带有C=O双键。
外部描述符（External Descriptors）	暂无

三维结构

交互式化学结构模型

球棍
棍棒
线框模型
空间填充
显示氢气
动画

化学和物理性质

溶解性

Soluble in DMSO, hot pyridine, acetonitrile, and most organic solvents. Insoluble in water.

密度

1.7

敏感性

对湿度、热敏感

折光率

1.6

沸点

383.7℃

熔点

188-191°C

分子量

256.170 g/mol

XLogP3

-1.300

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

256.033 Da

单同位素质量Monoisotopic Mass

256.033 Da

拓扑极表面积Topological Polar Surface Area

110.000 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

386.000

同位素原子数Isotope Atom Count

定义的原子立体中心计数Defined Atom Stereocenter Count

未定义的原子立体中心计数Undefined Atom Stereocenter Count

定义的键立体中心计数Defined Bond Stereocenter Count

未定义的键立体中心计数Undefined Bond Stereocenter Count

所有立体化学键的总数The total count of all stereochemical bonds

共价键合单元计数Covalently-Bonded Unit Count

安全和危险性（GHS）

象形图

GHS06, GHS07

信号词

危险

危险声明

H301: 吞咽会中毒

H302: 吞食有害

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激

预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P264: 处理后要彻底洗手。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P271: 仅在室外或通风良好的地方使用。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理（请参阅此标签上的...）。

P330: 漱口

P302+P352: 如皮肤沾染：用水充分清洗。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P405: 密闭存放

P403+P233: 存放在通风良好的地方。保持容器密闭。

P501: 将内容物/容器处理到。。。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P301+P316: 如果吞咽：立即寻求紧急医疗救助。

P301+P317: 如果被吞咽：请寻求医疗帮助。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。

WGK Germany

个人防护装备

dust mask type N95 (US),Eyeshields,Faceshields,Gloves

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到28个结果

批号(Lot Number)	证书类型	货号
L2215025	分析证书	D106171
L2215062	分析证书	D106171
G2624185	分析证书	D106171
G2624184	分析证书	D106171
G2624183	分析证书	D106171
G2624182	分析证书	D106171
F2610052	分析证书	D106171
A2623349	分析证书	D106171
G2601115	分析证书	D106171
A2623348	分析证书	D106171
A2623347	分析证书	D106171
A2623326	分析证书	D106171
L2107667	分析证书	D106171
D2524139	分析证书	D106171
D2524140	分析证书	D106171
D2524141	分析证书	D106171
D2524138	分析证书	D106171
A2607041	分析证书	D106171
I2510131	分析证书	D106171
G2322281	分析证书	D106171
H2316231	分析证书	D106171
G2322268	分析证书	D106171
L2214979	分析证书	D106171
L2215086	分析证书	D106171
I1817065	分析证书	D106171
G2230332	分析证书	D106171
G2230326	分析证书	D106171
G2230205	分析证书	D106171

显示更多⌵

技术文档和文章

吡咯烷及其衍生体系：五元含氮环如何通过“电荷态—构象—官能团换挡”把性质与用途调得更可控（附表1–表4选型导航）

目录：技术文章

探索主题:

吡咯烷

Pyrrolidine and Its Derivative Systems: How a Five-Membered N-Heterocycle Tunes Properties and Use Cases via “Charge State–Conformation–Functional-Group Switching” (with Tables 1–4 for Selection Navigation)

目录：技术文章

探索主题:

Pyrrolidine

DSC 的方法学价值：NHS 型活化中间体的构建与选用判断

目录：技术文章

探索主题:

DSC N,N′-二琥珀酰亚胺基碳酸酯

The Methodological Value of DSC: Building NHS-Type Activated Intermediates and Deciding When to Use Them

目录：技术文章

探索主题:

DSC N,N′-disuccinimidyl carbonate

五氟苯基体系的实验选用逻辑：从活性酯、预活化单体到下游转化的实验判断

目录：技术文章

探索主题:

五氟苯酚 PFP-OH 氟苯基酯 PFP esters

Experimental Selection Logic for Pentafluorophenyl-Based Systems: Practical Judgment from Active Esters and Pre-Activated Monomers to Downstream Transformations

目录：技术文章

探索主题:

Polypentafluorophenol PFP-OH PFP esters Pentafluorophenyl esters

三光气在有机合成中的实验判断：按反应任务理解其选用逻辑

目录：技术文章

探索主题:

有机合成三光气

Experimental Evaluation of Triphosgene in Organic Synthesis: Understanding Its Selection Logic Through Reaction Tasks

目录：技术文章

探索主题:

Organic synthesis Triphosgene

4-[(叔丁基二甲基硅基)氧基]丁-1-醇：作为单保护 1,4-丁二醇构件和受保护 C4 连接臂的实验选型判断

目录：技术文章

探索主题:

有机合成药物化学羟基保护基

4-[(tert-Butyldimethylsilyl)oxy]butan-1-ol: Experimental Selection Logic as a Monoprotected 1,4-Butanediol Building Block and a Protected C4 Linker

目录：技术文章

探索主题:

Organic synthesis Medicinal Chemistry Hydroxyl Protecting Groups

目录：技术文章

探索主题:

多肽合成

Formation and Control of Carboxyl- and Hydroxyl-Related Impurities in Peptide Synthesis — Using Asp/Glu and Ser/Thr Residue Side Reactions as Examples

目录：技术文章

探索主题:

Peptide synthesis Functional Group Carboxyl group

此产品的引用文献

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引用文献

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4. Wei Lu, Xiaoqiang Wang, Congyu Wang, Ke Gong, Jiawei Li, Xue Li, Peng Wang. (2023) A self-powered biosensor based on triboelectric nanogenerator for dual-specificity bacterial detection. InfoMat, [10.1002/inf2.12508]
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6. Zou Rong, Cao Lei, Wu Nan, Chang Gang, Li Li, Xiao Lu, Yan Huiling, Li Hongjie, Wang Ping, Bao Ting, Zhang Xiuhua, Wang Shengfu, Wang Yaping, He Hanping. (2023) Transistor-based immunosensor using AuNPs-Ab2-HRP enzyme nanoprobe for the detection of antigen biomarker in human blood. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, [PMID:37930375] [10.1007/s00216-023-05002-0]
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19. Guangwei Yang, Longxiang Tao, Guijie Kang, Jinhao Yan, Kewu He, Xuefu Wang, Jun Yin. (2023) Construction of Actively Targeted and High Drug Content Polyprodrug Amphiphiles to Perform Synergistic Chemo–Photo-Anti-Tumor Therapy and Immune-Activated Investigation. CHEMISTRY OF MATERIALS, [10.1021/acs.chemmater.3c00820]
20. Xuyan Lu, Zirui Liu, Qirui Jia, Qiusheng Wang, Qi Zhang, Xiaoran Li, Jianyong Yu, Bin Ding. (2023) Flexible Bioactive Glass Nanofiber-Based Self-Expanding Cryogels with Superelasticity and Bioadhesion Enabling Hemostasis and Wound Healing. ACS Nano, [PMID:37278622] [10.1021/acsnano.3c01370]
21. Hu Qing-Di, Jiang Hong-Liu, Lam Kwok-Ho, Hu Zhi-Peng, Liu Zhi-Jie, Wang Hua-Ying, Yang Yong-Yu, Baigenzhenov Omirserik, Hosseini-Bandegharaei Ahmad, He Fu-An. (2023) Polydopamine-modification of a magnetic composite constructed from citric acid–cross-linked cyclodextrin and graphene oxide for dye removal from waters. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (32): (78521-78536). [PMID:37271788] [10.1007/s11356-023-27679-7]
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