计算溶液所需的质量、体积或浓度。
有货
为什么选择此级别
冻干粉,天然,生物活性,高性能 级 提供 ≥50% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 3 篇同行评审文献引用。
概述
猪肾来源 D‑氨基酸氧化酶，可用于 D‑丙氨酸、黄素腺嘌呤二核苷酸（FAD）的测定，以及利用外消旋混合物制备 L‑氨基酸。本产品不用于制药用途。
D-Amino Acid Oxidase isolated from porcine kidney is used in the measurement of D-alanine and FAD, and in the preparation of L-amino acids from racemic mixtures. This product is not intended for use in pharmaceutical applications.
Applications
The measurement of d-alanine and fad, and in the preparation of l-amino acidsfrom racemic mixtures. Life Science.
规格
产品名称
D-氨基酸氧化酶
别名
D-α-氨基氧化酶 | D-氨基酸：氧气 氧化还原酶（脱氨）
英文别名
D-amino-acid oxidase | D-AAO | D-Amino acid: oxygen oxidoreductase (deaminating) | DAO | DAAO | DAO1 | DAMOX
规格或纯度
生物活性, 天然, 高性能, 冻干粉, ≥50%, 来源于猪肾脏; ≥6 U/mg enzyme powder
生化机理
Catalyzes the oxidative deamination of D-amino acids with broad substrate specificity. Required to catabolize D-amino acids synthesized endogenously, of gastrointestinal bacterial origin or obtained from the diet, and to use these as nutrients (By similarity). Regulates the level of D-amino acid neurotransmitters in the brain, such as D-serine, a co-agonist of N-methyl D-aspartate (NMDA) receptors, and may modulate synaptic transmission (By similarity). Catalyzes the first step of the racemization of D-DOPA to L-DOPA, for possible use in an alternative dopamine biosynthesis pathway (By similarity). Also catalyzes the first step of the chiral inversion of N(gamma)-nitro-D-arginine methyl ester (D-NNA) to its L-enantiomer L-NNA that acts as a nitric oxide synthase inhibitor (By similarity). The hydrogen peroxide produced in the reaction provides protection against microbial infection; it contributes to the oxidative killing activity of phagocytic leukocytes and protects against bacterial colonization of the small intestine. Enzyme secreted into the lumen of the intestine may not be catalytically active and could instead be proteolytically cleaved into peptides with antimicrobial activity (By similarity). The hydrogen peroxide produced in the reaction may also play a role in promoting cellular senescence in response to DNA damage (By similarity). Could act as a detoxifying agent which removes D-amino acids accumulated during aging (By similarity). Miscellaneous: Variation of pH perturbs the enantioselectivity of the enzyme towards some amino acids. Catalytic activity: a D-alpha-amino acid + O2 + H2O = a 2-oxocarboxylate + H2O2 + NH4+13 Publications1 PublicationThis reaction proceeds in the forward direction.
Post-translational: Phosphorylated in the cerebellum; probably not by PRKACA, PRKCA or PRKCE. May be S-nitrosylated, which partially inactivates the enzyme.
生物活性
≥6 U/mg enzyme powder
种属
猪(Pig)
来源
天然
CAS编号和信息
9000-88-8
分子类型
酶
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
浓度
来源于猪肾脏; ≥6 U/mg enzyme powder
复溶
Reconstitute in distilled water or dilute buffer.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
长期储存-20℃（24个月）；复溶后建议分装，避免反复冻融。
单位定义
在 pH 8.3、25 ℃条件下，存在过氧化氢酶（catalase）时，每分钟将 1 μmol D‑丙氨酸转化为丙酮酸所需的酶量。
技术文档
高级数据
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ26F0838474 |
分析证书 | D1518242 |
| ZJ26F0535642 |
分析证书 | D1518242 |
| ZJ26F0535643 |
分析证书 | D1518242 |
| ZJ26F0535644 |
分析证书 | D1518242 |
技术文档和文章
此产品的引用文献
溶液计算器
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