Dibenzocycolctyne PEG 马来酰亚胺, DBCO-PEG-Mal

货号: D163532
有货
级别和纯度: MW 1000 Da
储存条件
避光,-20°C储存,充氩
运输条件
超低温运输
★
规格
库存
价格
数量
5mg
D163532-5mg
期货 Stock Image
¥370.90
20mg
D163532-20mg
期货 Stock Image
¥1,139.90
100mg
D163532-100mg
现货 Stock Image
¥3,999.90
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概述

Maleimide PEG DBCO (dibenzocycolctyne) is one of Nanocs DBCO PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjμgation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Meanwhile, maleimide group can react with sulfhydryl (Thoil) groups at pH 6.5-7.5 easily. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Maleimide PEG DBCO (dibenzocycolctyne) is one of Nanocs DBCO PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Meanwhile, maleimide group can react with sulfhydryl (Thoil) groups at pH 6.5-7.5 easily. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

规格

规格或纯度
MW 1000 Da
英文名称
DBCO PEG Maleimide, DBCO-PEG-Mal
储存条件
避光,-20°C储存,充氩
运输条件
超低温运输
名称和识别符
分子类型
聚合物

高级数据

化学和物理性质
溶解性
Soluble in aqeous buffer and DMSO
敏感性
对光敏感
质检证书(CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
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找到5个结果

批号(Lot Number) 证书类型 货号
G2516289G2516289 分析证书 D163532
G2516290G2516290 分析证书 D163532
G2516291G2516291 分析证书 D163532
B2328630B2328630 分析证书 D163532
B2328624B2328624 分析证书 D163532
技术文档和文章
无铜点击化学
Copper-Free Click Chemistry
聚乙二醇修饰剂(PEG)的一般共轭反应——聚乙二醇马来酰亚胺(PEG-Mal)
General Conjugation Protocols of PEG linkers——PEG Maleimide
聚乙二醇马来酰亚胺试剂
PEG Maleimide reagents
聚乙二醇(PEG)及其衍生物:端基设计与在 PROTAC、ADC 和医疗器械中的应用
Polyethylene Glycol (PEG) and Its Derivatives: End-Group Design and Applications in PROTACs, ADCs, and Medical Device
DBCO PEG 马来酰亚胺(DBCO-PEG-Mal):选择与使用指南
DBCO PEG Maleimide (DBCO-PEG-Mal): Selection & Usage Guide
溶液计算器