MCM proteins

Applications of the MCM Protein Family in DNA Replication Licensing, Replication Stress, and Tumor Proliferation Research

The MCM protein family is a core component of DNA replication licensing and replication origin activation. MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7 jointly form the MCM2-7 complex, which is loaded onto replication origins in G1 phase and forms the CMG helicase with CDC45 and GINS in S phase, ...