Dual Vulnerabilities of MSI-H Tumors: Immune Responses and Synthetic Lethality with WRN
High microsatellite instability (microsatellite instability-high, MSI-H) is a genomic phenotype resulting from defective DNA mismatch repair. The continuous accumulation of insertion–deletion mutations generates frameshift neoantigens that increase tumor immune visibility while also producing ...
危险品化学品经营许可证（带存储）