Journal of Environmental Chemical Engineering
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2024
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IF 7.4
Jiaojiao Song,Ruiyan Wang,Jiale Wang,Yi Hu,Jiaxuan Guan,Yang Li,Xiangjian Xu,Qi Zhou
The exploration of the synthesis of porous carbon-supported metal nanocatalysts with high metal loading and dispersion for the development of heterogenous catalysts is important. However, this remains a challenging subject. In this paper, a salt template-assisted polymer tethering strategy was proposed to prepare Co single atom and ultrafine cluster anchored on porous carbon (Co-NPC) with a high-loading of 16.9 wt%, thereby exposing high density of reaction sites. The obtained Co-NPC catalyst exhibited excellent catalytic performance for almost 100 % degradation of bisphenol A (BPA) within 20 min, which is much faster than the Co SA -NPC catalyst with only single atom sites and Co-NC without salt template added. Radical quenching experiments and electron paramagnetic resonance tests verified that both the nonradical oxidation pathway by 1 O 2 , the electron transfer and radical oxidation pathway by •OH, SO 4 •- appeared during the degradation process. After 3 cycles, the removal rate of BPA did not decrease significantly. The fixed bed experiment revealed that Co-NPC could realize the continuous degradation of methylene blue (MB) with almost 100 % degradation efficiency. This research indicated that the strategy by pyrolyzing metal coordinated polymer is a potential method for the synthesis of high metal loading catalyst at gram scale, meeting the requirement of practical applications.
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APPLIED SURFACE SCIENCE
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2024
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IF 6.3
Yunyun Huang,Hongju Ren,Huihuang Fang,Dong Ouyang,Chongqi Chen,Yu Luo,Li Lin,Dabiao Wang,Lilong Jiang
Ammonia decomposition for onsite hydrogen production has been regarded as an important reaction which links to efficient hydrogen storage, transport and utilization. However, it still remains challenging to develop efficient catalysts with robust stability for ammonia decomposition. Herein, an integrated strategy was employed to synthesize Ru/SiO 2 @N-CS via wrapping a thin layer of N-doped carbon onto the SiO 2 sphere, following the anchor of Ru nanoparticles (NPs) onto the support. The obtained Ru/SiO 2 @N-CS (Ru loading: 1 wt%) shows a promising performance for ammonia decomposition, reaching 94.5 % at 550 °C with a gas hourly space velocity (GHSV) of 30 000 mL g cat -1 h −1 . The combination of the SiO 2 as the core prevents the degradation of N-doped carbon layers and then enhance the durability of the catalysts, remaining stable after 50 h at evaluated temperatures. Adequate characterizations were used to illustrate the effect of microchemical environment on ammonia decomposition activity of Ru/SiO 2 @N-CS catalyst under different calcination atmosphere and the correlation between structure and performance.
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JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
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2024
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IF 3.6
Shanjiang Chen,Jianjian Yang,Fuli Liu
Celastrol (CEL) belongs to the group of non-steroidal immunosuppressants with the potential to improve cardiac hypertrophy (CH). However, the poor biocompatibility and low bioavailability of CEL limit its in vivo application. This study was aimed to develop a targeted drug delivery system that can efficiently and safely deliver CEL to target tissues, providing a research basis for the application of CEL in CH therapy. A novel ROS-sensitive drug-loaded nanomicelle, dodecanoic acid (DA)-phenylboronic acid pinacol ester-dextran polymer encapsulating CEL (DBD@CEL), was synthesized using chemical synthesis. Then, the morphology, particle size, drug-loaded content, and ROS-responsive release behavior of DBD@CEL were studied. Pharmacokinetics and biocompatibility were evaluated using healthy mice. Finally, the ability and mechanism of DBD@CEL in improving CH in vivo were investigated using a mouse CH model. DBD@CEL was successfully prepared with a drug loading of 18.9%. It exhibited excellent stability with an average particle size of 110.0 ± 1.7 nm. Within 48 h, DBD@CEL released only 19.4% in the absence of H2O2, while in the presence of 1 mM H2O2, the release rate increased to 71.5%. Biocompatibility studies indicated that DBD@CEL did not cause blood cell hemolysis, had no impact on normal organs, and did not result in abnormal blood biochemical indicators, demonstrating excellent biocompatibility. In vivo studies revealed that DBD@CEL regulated the activation of NF-κB signaling, inhibits pyroptosis and oxidative stress, and thereby ameliorates CH. The ROS-responsive DBD@CEL nanodrug delivery system enhances the therapeutic activity of CEL for CH, providing a promising drug delivery system for the clinical treatment of CH.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Xin-yang Pan,Zi-han Wang,Xiao-qing Wu,Chang-rong Guo,Lin-xing Yang,Hui-ru Liu,Yuan-hao Wang,Wen-juan Chen,Jing-jie Wang,Kai-hui Nan,Ling-li Li
Reactive oxygen species (ROS) scavenging is a viable approach to promote corneal epithelium wound healing. This study created a single-component hydrogel (HA Gel) with a novel dual-functionalized hyaluronic acid derivative (HA-GA-PBA) containing gallol and phenylboronic acid (PBA) moieties. Both of these moieties were dual-functional. Specifically, they not only functioned as structural building blocks for hydrogel formation, but also served as bioactive ingredients for therapeutic purpose. Dynamic covalent complexation between gallol and PBA moieties led to the self-crosslinked HA Gel, which was antioxidative and tissue-adhesive. It was demonstrated that the hydrogel enhanced the proliferation rate of human corneal epithelial cells by over 2.5 folds. When treating the mouse corneal alkali burn model with HA Gel, the corneal epithelial healing percentages reached 69.19 ± 9.41 % and 84.12 ± 6.09 % on day 3 and 5, respectively, which were significantly higher than the placebo group (51.14 ± 9.63 % and 67.32 ± 10.54 % on day 3 and 5, respectively). Meanwhile, reduced scar formation and inflammation was observed. These findings indicated HA Gel could find applications in various of ocular diseases for improved corneal epithelial wound healing.
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CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Shuang Zhong,Yu Tian,Chen Chen,Bin Nie,Hongyan Wang,Shengyu Zhang
The utilization of nitrogen and sulfur-codoped biochar-activated peroxymonosulfate (PMS) has emerged as a promising advanced oxidation technology for the degradation of organic pollutants. However, the dominant active sites, especially the specific defect structures governing PMS activation and their subsequent activation mechanism remain ambiguous, posing challenges to the rational design of high-performance biochar catalysts. Herein, a series of nitrogen and sulfur-codoped biochar (NSBC) with varying pyrolysis temperatures and doping levels were synthesized. An investigation into the relationship between their properties and the reaction rate constants of 2,4-dichlorophenol (2,4-DCP) degradation by activated PMS revealed that intrinsic defects, thiophene S, and graphitic N were active sites in the oxidation reaction, with intrinsic defects identified as playing a predominant role. Density functional theory (DFT) calculations combined with electrochemical measurements further revealed the crucial role of single-vacancy defective configuration in mediating a direct electron transfer pathway for 2,4-DCP degradation. Moreover, double-vacancy and topological defects facilitated the transfer of electrons to adsorbed PMS, leading to the release of 1 O 2 and subsequent degradation of 2,4-DCP. The distinctive mechanism enabled the NSBC-activated PMS system to exhibit high selectivity and effectively remove 2,4-DCP from a complex aquatic environment. The findings from this study provide valuable insights into the role of specific structural defects in PMS activation and offer theoretical support for the design of biochar catalysts with heteroatom doping strategies.
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CORROSION SCIENCE
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2025
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IF 8.5
Min Gao,Chijia Wang,Weihao Fan,Haonan Liu,Yue Sun,Qianqian Yin,Zihua Wang,Zhanjian Liu,Ruitao Wang,Huaiyuan Wang
A novel three-dimensional cross-linked network structure is constructed in epoxy coatings through numerous chemical reactions within fillers and between filler and resin. The organic combination between fillers, resins and curing agents improves the coating compactness, the dense and stable "3D network" can effectively shield the CO 2 corrosion. Additionally, the excellent toughness of flexible Polyamide modified with polydopamine and the outstanding strength of rigid MoS 2 modified with KH560 significantly improve the wear resistance, impact resistance and thermal stability of coating. The EIS results obtain under CO 2 environments indicated the mixed coating impedance is approximately 1000 times higher than ordinary coating.
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INDUSTRIAL CROPS AND PRODUCTS
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2024
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IF 5.6
Jiahuan He,Chunhong Zhang,Yingying Wang,Yuning Gong,Lanyue Zhang,Hao Liu,A. Yuhui,Lei Shang
Advancing bio-based non-isocyanate polyurethanes (NIPUs) is vital for fostering sustainable development. This study, inspired by the concept of "rigid and flexible" successfully utilized resveratrol , epoxidized soybean oil, and carbon dioxide (CO 2 ) to produce a novel type of NIPUs (CRSOP) with outstanding mechanical properties, recyclability, and adhesive properties . Test results reveal that CRSOP demonstrates a tensile strength of 20.85 MPa and an elongation at break surpassing 160 %. The synthesized CRSOP shows excellent recyclability, with a recycling efficiency of over 80 % even after three cycles. Additionally, the rich polar groups in CRSOP contribute to its exceptional adhesion on diverse substrates such as copper (5.29 MPa), steel (7.48 MPa), aluminum (6.12 MPa), glass (4.71 MPa), and polytetrafluoroethylene (1.75 MPa). Even after prolonged immersion in organic solvents , CRSOP maintains a lap shear strength comparable to the initial value, demonstrating outstanding environmental tolerance. This paper showcases a superior-performing NIPUs derived from renewable resources and simultaneously expands its extensive application in the adhesive field.
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2024
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IF 6.2
Yang Liu,Xia Wang,Bo Pan,Zhuo Wei,Jing Zhao,Hao Qiu,Christian E.W. Steinberg,Willie J.G.M. Peijnenburg,Martina G. Vijver
A suspension of copper oxide nanoparticles (CuO NPs) is a mixture of dissolved and particulate Cu, the relative proportions of which highly depend on the water chemistry. However, the relationship between different proportions of particulate and dissolved Cu and the overall toxicity of CuO NPs is still unknown. This study investigated the response of Chlorella vulgaris to CuO NPs at varying solution pH and at different tannic acid (TA) additions, with a focus on exploring whether and how dissolved and particulate Cu contribute to the overall toxicity of CuO NPs. The results of the exposure experiments demonstrated the involvement of both dissolved and particulate Cu in inducing toxicity of CuO NPs, and the inhibition of CuO NPs on cell density of Chlorella vulgaris was found to be significantly ( p < 0.05) alleviated with increased levels of TA and pH (< 8). Using the independent action model, the contribution to toxicity of particulate Cu was found to be enhanced with increasing pH values and TA concentrations. The toxic unit indicator better ( R 2 = 0.86, p < 0.001) explained impacts of CuO NPs on micro-algae cells than commonly used mass concentrations ( R 2 = 0.27–0.77, p < 0.05) across different levels of pH and TA. Overall, our study provides an additivity-based method to improve the accuracy of toxicity prediction through including contributions to toxicity of both dissolved and particulate Cu and through eliminating the uneven distribution of data due to large variations in total Cu, particulate Cu, dissolved Cu, Cu 2+ activities, Cu-TA complexes and other Cu-complexes concentrations with varying water chemistry conditions.
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Journal of Water Process Engineering
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2024
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IF 6.3
Can Cai,Longfei Gao,Yuzhu Xiong
In this work, Fe 3 O 4 magnetic particles were in-situ grown on the surface of Montmorillonite (MTT) via co-precipitation method, and a green, recyclable chitosan (CS)/carboxymethyl cellulose (CMC)/sodium alginate (SA)/MMT-Fe 3 O 4 double network (DN) hydrogel (C-M-SD/MMT-Fe 3 O 4 ) was successfully synthesized. The magnetization of MMT-Fe 3 O 4 addition improved the maximum compressive strength of CS/CMC/SA double network hydrogel (C-M-SD), reaching 17.13 kPa. The adsorption capacities of the magnetized DN hydrogel for methylene blue (MB) and Cu 2+ were 224.49 mg/g and 121.15 mg/g, respectively. Moreover, cytotoxicity tests using CCK8 solution showed that the cell activity was >80 % after 24 h culture in the prepared hydrogel extracts, which demonstrated that the prepared hydrogel adsorbent did not release any toxic substances into the water source throughout the adsorption process . It can be concluded from the Vibrating Sample Magnetometer (VSM) that the saturation magnetization of the prepared magnetic double-network hydrogel reaches 15 emu/g and the coercivity is 0, showing the superparamagnetism . The synthesized C-M-SD/MMT-Fe 3 O 4 hydrogel possesses excellent mechanical properties, natural degradability, recyclability and biocompatibility, making it an ideal candidate for wastewater treatment applications.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Xueying Song,Xingyan Wei,Liu Liu,Yongfeng Liu
In this study, linalool-nanoparticles (L-NPs) were prepared (encapsulation efficiency was 68.54 %) and introduced pH-indicator film based on cranberry-extract (CEF) to develop multifunctional smart films. XRD analysis and FTIR spectroscopy indicated that cranberry-extract (CE) and L-NPs were uniformly distributed in the gelatin/agar matrix and could change the intermolecular structure of the film. Color change of smart films showed that CE endowed the film with pH-sensitive property. As CE and L-NPs were added to the film, the water contact angle (WCA) was increased from 57.03° to 117.73°, the elongation at break (EAB) was increased from 12.30 % to 34.60 %. Additionally, the introduction of L-NPs enhanced the antioxidant activity (DPPH free radical scavenging rate increased from 26.80 % to 36.35 %) and antibacterial activity (against S. aureus and E. coli ) of the smart film, which were verified by its retarding effect on pork spoilage.
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JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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2025
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IF 3.1
Dong-shuo Meng,Guo-jing Li,Shen-guo Sun,Chun-xin Ma,Tian-quan Zhu,Yu Liu
A series of GC-FID and HPLC-RID methods were developed and rigorously validated for the detection of various aldehyde and ketone impurities, including 5-methyl-2-hexanone and 5-methyl-3-hexen-2-one, as well as quaternary ammonium salt impurity that lack UV absorption, during the synthesis of tetrabenazine. Six novel compounds, three have not been previously reported, were synthesized and their structures confirmed. This was achieved through a comprehensive investigation into impurity transmission chains and their clearance throughout the synthesis process. The limits for all detected impurities, which included a total of twelve related substances, were established at approximately 0.1 %. The LOD for the developed analytical methods ranged from 0.3 μg mL −1 to 12.5 μg mL −1 .
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Food Chemistry-X
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2024
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IF 6.5
Jinman He,Wanli Zhang,Gulden Goksen,Mohammad Rizwan Khan,Naushad Ahmad,Xinli Cong
In this study, zein-pectin nanoparticles loaded with Wampee [ Clausena lansium (Lour.) Skeels] (WEO) were developed. The particle size of the nanoparticles is 515.9 nm, polydispersity index is 0.4 and zeta potential is −39.3 mV. Subsequently, the ZWP was incorporated into sodium alginate (SA)-based film (ZWP-S). The films were then analyzed to determine their physical properties and thermal stability, and also to examine their microstructure and intermolecular forces using SEM, FTIR, and XRD techniques. Additionally, the films were evaluated for their antimicrobial and antioxidant activity, as well as their ability to sustain the release of WEO. Overall, the ZWP-S film conferred excellent functional properties, including UV barrier performance, mechanical properties (21 % increase in tensile strength), water sensitivity, stability, more compact structure, high antioxidant activity and long-lasting antimicrobial activity, surpassing those of the control film. Consequently, it was applied as a novel coating for preserving strawberries, rotting rate of strawberries was reduced by 43 % at 6d, yielding promising results in prolonging the freshness of the fruit.
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