Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe³⁺. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergens from serum.

规格

产品名称

Native Rat Transferrin Protein

别名

转铁蛋白来源于大鼠血清 | 大鼠转铁蛋白 | 天然大鼠转铁蛋白 | β₁- 金属结合球蛋白 | 嗜铁蛋白

英文别名

规格或纯度

无载体,≥95%(SDS-PAGE),来源于大鼠血清; 蛋白浓度: 见COA

生化机理

Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

种属

大鼠(Rat)

Accession #

P12346

来源

天然

预测分子量

77 kDa

CAS编号和信息

11096-37-0

分子类型

蛋白质

储存与运输

物理形态

液体

储存缓冲液

PBS, pH 7.4.

浓度

来源于大鼠血清; 蛋白浓度: 见COA

储存条件

-20°C储存,避免反复冻融

运输条件

超低温运输

稳定性与储存

长期储存-20℃或-80℃（6个月）；收货后建议分装，避免反复冻融。

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

查询 COA →

📊 产品数据表

产品规格和应用的快速参考摘要。

查看数据表 →

🔬 规格说明书

该级别的完整质量属性和验收标准。

查看规格说明 →

高级数据

产品属性

ALogP	-2.5

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

技术文档和文章

np001009_transferrin, rat plasma.pdf

链霉亲和素修饰蛋白的专业指南

目录：技术文章

探索主题:

亲和素链霉亲和素

Professional Guide to Streptavidin-Modified Proteins

目录：技术文章

探索主题:

Avidin Streptavidin

蛋白质分子量标准

目录：技术文章

探索主题:

蛋白质蛋白质分子量标准

Protein Molecular Weight Standards

目录：技术文章

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protein Protein Molecular Weight Standards

转铁蛋白与脱铁转铁蛋白：结构特征、铁稳态机制与应用技术要点

目录：技术文章

探索主题:

细胞培养转铁蛋白脱铁转铁蛋白铁饱和度转铁蛋白受体受体介导内吞靶向递送

Transferrin and Apo-Transferrin: Structural Features, Iron-Homeostasis Mechanisms, and Key Technical Application Points

目录：技术文章

探索主题:

cell culture Transferrin apo-transferrin transferrin saturation transferrin receptor receptor-mediated endocytosis targeted delivery

此产品的引用文献

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引用文献

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2. Tongtong Hou, Xu Shao, Minling Ding, Kun Mei, Xin Wang, Ping Guan, Xiaoling Hu. (2023) Photooxidative inhibition and decomposition of β-amyloid in Alzheimer's by nano-assemblies of transferrin and indocyanine green. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:37086772] [10.1016/j.ijbiomac.2023.124432]
3. Shiwei Liu, Shuang Han, Yuzhuo Song, Ruonan Sun, Le Zhao, Chen Yan. (2023) Disulfide-Bridged Dendritic Organosilicas-Based Biodegradable Molecularly Imprinted Polymers for Multiple Targeting and pH/Redox-Responsive Drug Release toward Chemical/Photodynamic Synergistic Tumor Therapy. Advanced Healthcare Materials, 12 (20): (2300184). [PMID:36943098] [10.1002/adhm.202300184]
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5. Ji Feng, Shuai Chen, Yong-Liang Yu, Jian-Hua Wang. (2020) Red-emission hydrophobic porphyrin structure carbon dots linked with transferrin for cell imaging. TALANTA, [PMID:32498886] [10.1016/j.talanta.2020.121014]
6. Yameng Han, Tianyu Chen, Yiliang Li, Langxing Chen, Lin Wei, Lehui Xiao. (2019) Single-Particle Enumeration-Based Sensitive Glutathione S-Transferase Assay with Fluorescent Conjugated Polymer Nanoparticle. ANALYTICAL CHEMISTRY, [PMID:31402640] [10.1021/acs.analchem.9b01849]
7. Wei Chen, Min Fu, Xixi Zhu, Qingyun Liu. (2019) A close-packed imprinted colloidal array for naked-eye detection of glycoproteins under physiological pH. BIOSENSORS & BIOELECTRONICS, [PMID:31306955] [10.1016/j.bios.2019.111499]
8. Qiao Juan, Liu Qianrong, Wu Han, Cai Huiwu, Qi Li. (2019) Non-enzymatic detection of serum glucose using a fluorescent nanopolymer probe. MICROCHIMICA ACTA, 186 (6): (1-7). [PMID:31114937] [10.1007/s00604-019-3475-9]
9. Xiaoting Xue, Rui Lu, Min Liu, Yi Li, Jiansheng Li, Lianjun Wang. (2018) A facile and general approach for the preparation of boronic acid-functionalized magnetic nanoparticles for the selective enrichment of glycoproteins. ANALYST, 144 (2): (641-648). [PMID:30475352] [10.1039/C8AN01704B]
10. Wenhui Fu, Fei Qu, Gang Yu, Jinmao You. (2017) High selectivity for sodium dodecyl sulphate by polymer nanoparticles and detection of proteins based on the polymer nanoparticles-sodium dodecyl sulphate system. SENSORS AND ACTUATORS B-CHEMICAL, [10.1016/j.snb.2017.01.175]
11. Fei Qu, Xinyu Guo, Dongya Liu, Guang Chen, Jinmao You. (2016) Dual-emission carbon nanodots as a ratiometric nanosensor for the detection of glucose and glucose oxidase. SENSORS AND ACTUATORS B-CHEMICAL, [10.1016/j.snb.2016.04.085]
12. Fei Qu, Dongya Liu, Jinmao You. (2016) Fluorescent turn-off/on bioassay for hemoglobin based on dual-emission carbon nanodots-graphene oxide system with multi-detection strategies. ANALYTICA CHIMICA ACTA, [PMID:27126790] [10.1016/j.aca.2016.03.048]
13. Jia Hao, Shaohui Beng, Zifeng Ma, Hongmei Xu, Ting Yang, Qiman Yang, Yunduan Wang, Wenhui Zheng, Yisha Ma, Shuo Zhang, Liangde Kuang, Wei Fu. (2024) Short-Term Exposure of Bisphenol A Deteriorates the Quality of Rabbit Milk by Impairing Milk Fat Synthesis. Food Science & Nutrition, [PMID:39723079] [10.1002/fsn3.4561]
14. Ma Zifeng, Li Qiao, Xu Hongmei, Li Yueyue, Wang Shujin, Xiong Yan, Lan Daoliang, Li Jian, Xiong Xianrong, Fu Wei. (2024) Zearalenone Triggers Programmed Cell Death and Impairs Milk Fat Synthesis via the AKT-mTOR-PPARγ-ACSL4 Pathway in Bovine Mammary Epithelial Cells. JOURNAL OF ANIMAL SCIENCE, [PMID:39285681] [10.1093/jas/skae276]
15. Yinuo Yuan, Liya Tian, Xinyu Liu, Kai Guo, Ke Ren, Lei Yan, Mengyao Mu, Shangui Liu, Feifei Teng, Cun Liu, Ping Liang, Xiao Sun. (2025) Transferrin-Targeted Nanoarchitectonics with Efficient Metastasis Inhibition Enabling Tumor T1-T2 Dual-Mode Magnetic Resonance Contrast Enhancement. Advanced Healthcare Materials, [PMID:40693301] [10.1002/adhm.202500690]
16. Mengjun Wang, Linyu Nian, Shuo Zhang, Yan Zeng, Wei Man, Xiaoyang Sun, Suilou Wang, Chongjiang Cao. (2025) Probiotics Behavior-Inspired Biomimetic Platform for Ulcerative Colitis Prevention and Therapy. ADVANCED FUNCTIONAL MATERIALS, [10.1002/adfm.202505817]
17. Kaimin Gong, Xiaofei Wang, Yunfeng Bai, Xueqin Ma, Guoning Chen. (2025) Preparation of In-Situ Multifunctional Silicon Self-Assembled Molecularly Imprinted Polymers for Selective Extraction of Protein. JOURNAL OF SEPARATION SCIENCE, 48 (10): (e70291). [PMID:41057285] [10.1002/jssc.70291]
18. Yan Hao, Zhendong Jiang, Yanxin Lu, Bin Zhou. (2025) Dual electrochemiluminescence signal sensor for simultaneous analysis of multiple tuberculosis biomarkers. MICROCHEMICAL JOURNAL, [10.1016/j.microc.2025.115711]
19. Yanbing Song, Zhuo Zhao, Yuxuan Wang, Ran Cheng, Yafei Wang, Yan Zhang, Ying Guan, Yongjun Zhang. (2026) Rational Engineering of Copper Ion-Coordinated Molecularly Imprinted Polymers for Synergistic Enhancement of Protein Recognition and Separation. LANGMUIR, [PMID:41661287] [10.1021/acs.langmuir.5c05246]