转铁蛋白是一种存在于血浆中的单体糖蛋白，平均浓度为250 mg/100 ml，是血浆中特异性的铁结合蛋白，参与铁在机体各器官间的运输和分配，参与铁的代谢，并通过肾脏防止铁的流失。作为tf结合铁储存在骨髓中，它还具有抑菌和抑菌活性。
作为一种在特定培养基中使用的重要运输因子，所有类型的细胞都需要转铁蛋白才能最大限度地生长。

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100 ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and prevention of iron loss via the kidneys. Stored in bone marrow as Tf-bound iron, it also possesses bacteriostatic and fungistatic activity.

An important transport factor used in defined culture media, transferrin is required by all types of cells for maximal growth.

Aladdin purifies transferrin from plasma that has been tested by FDA-required methods and found negative at the donor level for HIV 1&2 antibodies, Hepatitis B surface antigen, Hepatitis C antibodies, HAV (NAT), HBV (NAT), HCV (NAT), HIV (NAT), parvovirus B19 (NAT), and Syphilis.

Purity: ≥98% by SDS PAGE

Iron Content: ≥1200 μg/g

Heat-treated at 60°C for 10 hours.

Lyophilized from sterile de-ionized water after filtration using a 0.1 micron filter.

Readily soluble at 1% in water.

Endotoxin level: <1 EU/mg by LAL testing

Bioburden: <10 CFU/mg; Mycoplasma: None Detected

规格

产品名称

转铁蛋白来源于人血浆

英文别名

Serotransferrin | TF | TFQTL1

规格或纯度

BioReagent,天然,低内毒素,生物工艺级,≥98%(SDS-PAGE),铁含量：≥1200μg/g ; 冻干前浓度：见COA

生化机理

Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (Microbial infection) Serves as an iron source for Neisseria species, which capture the protein and extract its iron for their own use. (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use.

种属

人(Human)

来源

天然

预测分子量

80 kDa

分子类型

蛋白质

产品线

生物产品

储存与运输

物理形态

冻干(Lyophilized)

储存缓冲液

Lyophilized from sterile de-ionized water after filtration using a 0.1 micron filter.

浓度

铁含量：≥1200μg/g ; 冻干前浓度：见COA

复溶

After centrifugation, we suggest addition of de-ionized H2O to the original volume (See COA), followed by gentle mixingto ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.

储存条件

-20°C储存,避免反复冻融

运输条件

超低温运输

稳定性与储存

长期储存-20℃（＞1年）；复溶后建议分装，避免反复冻融。

高级数据

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

技术文档和文章

np001010_transferrin from human plasma.pdf

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转铁蛋白与脱铁转铁蛋白：结构特征、铁稳态机制与应用技术要点

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溶液计算器