α1-抗胰蛋白酶 来源于人血浆

CAS: 9041-92-3 货号: np001161
有货
级别和纯度: 生物活性 ? 生物活性级(Bioactive)—— 经验证在功能检测中保持生物活性。当分子须具有功能活性而不仅是纯度时使用。 ActiBioPure™ ? ActiBioPure™ —— 阿拉丁面向生物活性和重组产品的优质系列。当同时需要高纯度和保持生物活性时使用。 高性能 ? 高性能级 —— 纯度和性能特性经过优化。适用于普通等级无法满足的灵敏分析。 PBS Only ? 仅 PBS 配方 —— 以磷酸盐缓冲液供应,不含其他添加剂。当需要不含稳定剂/载体的洁净 PBS 缓冲液时使用。 ≥95%(SDS-PAGE) Pre-lyophilization Protein Concentration
Accession #
P01009
生物活性
When tested with active-site titrated porcine pancreatic trypsin using Na-Benzoyl-L-Arginine-para-Nitroanilide Hydrochloride (L-BAPNA) as substrate, it is 75-100% inhibitory.
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规格
库存
价格
数量
250μg
np001161-250μg
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¥899.90
1mg
np001161-1mg
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¥2,599.90
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为什么选择此级别

ActiBioPure™,PBS Only,生物活性,高性能 级 提供 ≥95%(SDS-PAGE) 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。

概述


Purified Native Human Alpha 1 Antitrypsin, Human Plasma
An acute-phase plasma protein found at 95-350 mg per 100 ml that functions as a protease inhibitor. Clinically, its deficiency is associated with two major diseases: pulmonary emphysema and early onset/juvenile hepatic cirrhosis. It is elevated in inflammatory conditions, malignancies, liver disease and pregnancy and also after surgical trauma and use of oral contraceptives. The simultaneous quantitative determination of alpha-1-PI and ceruloplasmin permits differential diagnosis of liver afflictions.
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
For research use or for use in further manufacturing.

规格

产品名称
α1-抗胰蛋白酶 来源于人血浆
别名
丝氨酸蛋白酶抑制剂A1 | α-1-抗胰蛋白酶 | α1抗胰蛋白酶 | α1-蛋白酶抑制剂
英文别名
α1-Proteinase inhibitor, A1PI, AAT | α1-Antitrypsin | Serpin A1 | alpha-1-Antitrypsin | Alpha 1 Antitrypsin | A1A | A1AT | AAT | MGC23330 | alpha 1-Antitrypsin | alpha 1-Proteinase Inhibitor | Alpha-1 protease inhibitor | Alpha-1-antiproteinase | antitryp
规格或纯度
生物活性,ActiBioPure™,高性能,PBS Only,≥95%(SDS-PAGE),Pre-lyophilization Protein Concentration
生化机理
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.Short peptide from AAT: Reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE). Miscellaneous: The aberrant form is found in the plasma of chronic smokers, and persists after smoking is ceased. It can still be found ten years after smoking has ceased.
生物活性
When tested with active-site titrated porcine pancreatic trypsin using Na-Benzoyl-L-Arginine-para-Nitroanilide Hydrochloride (L-BAPNA) as substrate, it is 75-100% inhibitory.
种属
人(Human)
来源
天然
预测分子量
52 kDa
CAS编号和信息
9041-92-3
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 30 mM Na phosphate, 300 mM NaCl, pH 6.5.
浓度
Pre-lyophilization Protein Concentration
复溶
After centrifugation, we suggest addition of de-ionized H2O to the original volume (See COA), followed by gentle mixingto ensure adequate homogenization. If further dilution is required, we suggest using the lyophilization buffer.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
长期储存-20℃(2年);复溶后建议分装,避免反复冻融。

技术文档

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高级数据

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找到6个结果

批号(Lot Number) 证书类型 货号
ZJ26F0737789 分析证书 np001161
ZJ26F0737788 分析证书 np001161
ZJ26F0232343 分析证书 np001161
ZJ26F0232342 分析证书 np001161
ZJ25F0825187 分析证书 np001161
ZJ25F0825186 分析证书 np001161
技术文档和文章
BRET(生物发光共振能量转移)方法
BRET (Bioluminescence Resonance Energy Transfer) Method
酶保护剂及延长酶活性的常用方法
Enzyme Protectants and Common Methods to Prolong Enzymatic Activity
红细胞裂解液技术说明与操作指南
Red Blood Cell Lysis Buffer — Technical Description & Operating Guide
胰蛋白酶与重组胰蛋白酶药典标准比较
Comparison of Pharmacopoeial Standards for Trypsin and Recombinant Trypsin
肽图检查法鉴定蛋白质结构
Peptide Mapping for Protein Structure Identification
丝氨酸内切蛋白酶的催化机制、分类特征与实验应用
Catalytic Mechanisms, Classification Characteristics, and Experimental Applications of Serine Endopeptidases
溶液计算器