Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using bovine EJG cells is less than 2.0 μg/ml, corresponding to a specific activity of > 500 IU/mg.
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
Endocrine gland-derived vascular endothelial growth factor (EG-VEGF), also called prokineticin 1 (PK1), is a member of the prokineticin family of secreted proteins that share a common structural motif containing ten conserved cysteine residues that form five pairs of disulfide bonds.
规格
产品名称
Recombinant Human EG-VEGF Protein
别名
重组人内分泌腺来源血管内皮生长因子(EG-VEGF) | 重组人EG-VEGF蛋白
英文别名
EGVEGF | EG-VEGF | EGVEGFblack mamba toxin-related protein | Endocrine-gland-derived vascular endothelial growth factor | Mambakine | PK1mambakine | PRK1prokineticin-1 | PROK1 | Prokineticin 1 | Black mamba toxin related protein | EG VEGF | PK1 | PRK1 | P
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using bovine EJG cells is less than 2.0 μg/ml, corresponding to a specific activity of > 500 IU/mg.
Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4, 0.02 % Tween-20.
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Recombinant Human EG-VEGF Protein (rp145479)-Protein Bioactivity Fully biologically active when compared to standard. The ED₅₀ as determined by a cell proliferation assay using bovine EJG cells is less than 2.0 μg/mL, corresponding to a specific activity of > 500 IU/mg.
Recombinant Human EG-VEGF Protein (rp145479)-SDS-PAGE Recombinant Human EG-VEGF Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining. Showing a band at 10.7 kDa under reducing conditions and 14.5-21.4 kDa under non-reducing conditions.