Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 6-36 ng/mL in the presence of 3 ng/mL of recombinant human Activin A.
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6.
规格
产品名称
Recombinant Mouse Activin RIIA Protein
别名
激活素A受体ⅡA(ACVR2A)重组蛋白
英文别名
activin A receptor, type II | activin A receptor, type IIA | Activin receptor type IIA | activin receptor type-2A | Activin RIIA | ActivinRIIA | ACTRII | ACTRIIA | ACVR2A | ACTR-IIA | AVR2A | EC 2.7.11 | EC 2.7.11.30 | Acvr2 | TactrII
Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 6-36 ng/mL in the presence of 3 ng/mL of recombinant human Activin A.
25 - 35 kDa, under reducing conditions; 25 - 35 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Mouse Activin RIIA Protein (rp164335) - SDS-PAGE 2 μg/lane of Mouse Activin RIIA Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 25 - 35 kDa.
ZJ25F0420506
危险品化学品经营许可证（带存储）