Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin (PFR-AMC). The specific activity is >1,000 pmol/min/µg, as measured under the described conditions.
Function Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
规格
产品名称
Recombinant Human Plasma Kallikrein/KLKB1 Protein
规格或纯度
无动物源,无载体,生物活性,ActiBioPure™,His标签,≥90%(SDS-PAGE)
生物活性
Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin (PFR-AMC). The specific activity is >1,000 pmol/min/µg, as measured under the described conditions.
80 kDa, under reducing conditions; 75 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human Plasma Kallikrein/KLKB1 Protein (rp167404) - SDS-PAGE 2 μg/lane of Recombinant Human Plasma Kallikrein/KLKB1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 80 kDa under reducing condition and 75 kDa under non-reducing condition.