Purity: ≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Deubiquitination is a critical regulatory process in the ubiquitin-proteasome pathway. Ubiquitin C-terminal hydrolases (UCHs) are a family of cysteine proteases that catalyze the hydrolysis of a peptide bond at the C-terminal glycine of ubiquitin. Members of the UCH family have been implicated in a number of human diseases, including neurodegenerative diseases and cancers. Mutations of the UCH-L1 gene and alterations of the protein activity have been found to be associated with several neurodegenerative disorders, including Parkinson’s, Huntington’s and Alzheimer’s diseases. It is also implicated in cancer tumorigenesis, including lung, breast, liver, kidney, colorectal and ovarian cancers. UCH-L1 is thought to be a tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors.
25.6 kDa, under reducing conditions; 25.6 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 50mM Tris, 150mM NaCl, 4% trehalose, pH 8.0
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human UCH-L1/PGP9.5 Protein (rp183597) - SDS-PAGE 3 μg/lane of Recombinant Human UCH-L1/PGP9.5 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 25.6 kDa.
ZJ24F0708013
危险品化学品经营许可证（带存储）