计算溶液所需的质量、体积或浓度。
| 活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
|---|
有货
为什么选择此级别
Moligand™ 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
-80℃储存。特低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 34 篇同行评审文献引用。
概述
易溶于水、甲醇、热乙醇、热丙醇、热丙酮、热乙酸乙酯、吡啶、冰醋酸中，少量溶于热的氯仿中。水中溶解度:46 g/L (20°C)。 Thymidine is also referred to as pyrimidine deoxynucleoside. Deoxythymidine is a nucleoside present in DNA. In a DNA double stranded structure, thymidine pairs with deoxyadeninosine. It is useful in cell synchronization during S-phase. In the salvage pathway of pyrimidines, pyrimidine phosphorylase reversibly converts thymine to thymidine.主要用于抗艾滋病药物（如齐多呋啶、石达呋啶）的制备 Thymidine (dT) is a pyrimidine deoxyriboside (deoxynucleoside) that upon sequential phosphorylation to deoxythymidine triphospate (dTTP) is used to synthesize DNA and the T-loop of transfer RNA. Thymidine is as substrate of Thymidine kinase EC 2.7.1.21 which phosphorylates the nucleoside with a phosphate derived from ATP. dT may be used to study the distribution, specificity and kinetics of a family of thymidine kinase(s). Thymidine has been used: · as a supplement in HL5-modified medium for cell culture · to incubate cells in cell-cycle analysis · in cell synchronization
Information
Thymidine (Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd, NSC 21548) is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in th
In vitro
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:
规格
规格或纯度
Moligand™, 10mM in DMSO
英文名称
Thymidine (NSC 21548)
生化机理
嘧啶脱氧核苷。强大的胸苷激酶底物（IC 50 = 16 nM）。与双链DNA中的脱氧腺苷配对。在体内同步S期的细胞。
储存条件
-80℃储存
运输条件
特低温运输
名称和识别符
EC号
200-070-4
分子类型
小分子
Isomeric SMILES
CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O
分子量
242.23
Beilstein号
89285
Reaxy-Rn
889638
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=889638&ln=
技术文档
高级数据
关联靶点（人）
TK1
Tchem
胸苷激酶，细胞质(Thymidine kinase, cytosolic)
(0 活性数据)
化学和物理性质
比旋光度
33 ° (C=1, 1mol/L NaOH)
熔点
183-191°C
安全和危险性（GHS）
WGK Germany
3
RTECS
XP2071000
Merck Index
9397
个人防护装备
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 J2225458 |
分析证书 | T407939 |
技术文档和文章
Mechanisms of Action, Research Applications, and Cold-Induced Effects of Colchicine: An Overview
目录： 技术文章
Pyrimidine Research Selection Guide: Structural Features, Typical Applications, and a Reagent/Building-Block Classification Navigator (Tables 1–5)
目录： 技术文章
Functional Systems of Nucleoside Metabolism-Related Enzymes in Drug Response and Disease Biology
目录： 技术文章
The Methodological Value of TPS-Cl: The Logic of Selective Activation and Representative Transformations in Nucleoside and Nucleotide Chemistry
目录： 技术文章
Coupling Activators, Nucleoside Building Blocks, and Modification Design in Oligonucleotide Chemical Synthesis: Their Effects on Synthetic Efficiency, Purity, and Product Properties
目录： 技术文章
此产品的引用文献
溶液计算器
产品仅提供给经过验证的企业、机构和合格的专业人员用于研发。不适用于人类、动物、诊断或治疗。
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