30 kDa adipocyte complement related protein antibody|30 kDa adipocyte complement-related protein antibody|ACDC antibody|Acrp 30 antibody|ACRP30 antibody|Adipocyte antibody|Adipocyte C1q and collagen domain containing protein antibody|Adipocyte complement related 30 kDa protein antibody|Adipocyte complement related protein of 30 kDa antibody|Adipocyte complement-related 30 kDa protein antibody|adipocyte-specific secretory protein antibody|Adiponectin antibody|Adiponectin precursor antibody|adiponectin, C1Q and collagen domain containing antibody|Adipoq antibody|Adipose most abundant gene transcript 1 antibody|Adipose most abundant gene transcript 1 protein antibody|Adipose specific collagen like factor antibody|ADIPQTL1 antibody|ADPN antibody|APM 1 antibody|apM-1 antibody|APM1 antibody|C1q and collagen domain-containing protein antibody|GBP 28 antibody|GBP28 antibody|Gelatin binding protein 28 antibody|gelatin-binding protein 28 antibody|Gelatin-binding protein antibody|OTTHUMP00000210047 antibody|ADIPOQ|ACDC|ADPN|APM1|APM-1|GBP28|ACRP30|ADIPQTL1
规格或纯度
≥90%(SDS-PAGE), 见COA
生化机理
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.