ExactAb™,已验证,无载体 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Mouse monoclonal (6H6H10) to CD42b, could be used for WB, Flow and ELISA.
Application:
WB: 1/500 - 1/2000; Predicted molecular weight: 72 kDa.
Flow: 1/200 - 1/400
ELISA: 1/10000
Protein Function:
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.
CD42b Mouse mAb (Ab094818) - Western Blot
All lanes: CD42b Mouse mAb (Ab094818) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/50000 dilution
Predicted band size: 72 kDa
Observed band size: 72 kDa
CD42b Mouse mAb (Ab094818) - Flow Cytometry
Flow cytometric analysis of HL-60 (human promyelocytic leukemia cell line) cells labeling CD42b with CD42b Mouse mAb (Ab094818) at 1/200 dilution (green) compared with a negative control (red).
CD42b Mouse mAb (Ab094818) - Flow Cytometry
Flow cytometric analysis of Jurkat (human T cell leukemia cell line from peripheral blood) cells labeling CD42b with CD42b Mouse mAb (Ab094818) at 1/200 dilution (green) compared with a negative control (red).
1/200-1/400
1/10000
1/500-1/2000; Predicted molecular weight:72 kDa.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ23F0700704 |
分析证书 | Ab094818 |
| ZJ23F0700705 |
分析证书 | Ab094818 |
| ZJ24F1011952 |
分析证书 | Ab094818 |
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