Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.
Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.
Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
宿主种属
小鼠(Mouse)
特异性
Human IL18
种属反应性
人(Human)
预测反应种属
Pan troglodytes
免疫原
Recombinant protein corresponding to Human IL-18
阳性对照
WB: A431 and U-2 OS whole cell lysates
偶联
Unconjugated
克隆类型
单克隆抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
1.0 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 7.2
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
图片
IL-18 Mouse mAb (Ab168999) - Western Blot All lanes: IL-18 Mouse Antibody (Ab168999) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 22 kDa Observed band size: 22 kDa Exposure time: 10.0 s
IL-18 Mouse mAb (Ab168999) - Western Blot All lanes: IL-18 Mouse Antibody (Ab168999) at 1/10000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 22 kDa Observed band size: 22 kDa Exposure time: 15.0 s