2410008N15Rik antibody | Constitutive heat shock protein 70 antibody | Epididymis luminal protein 33 antibody | Epididymis secretory sperm binding protein Li 72p antibody | Heat shock 70 kDa protein 8 antibody | Heat shock 70kD protein 10 antibody | Heat
规格或纯度
PBS Only, ExactAb™, 已验证, 无载体, 无叠氮钠, 重组, 见COA
生化机理
Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing the co-chaperones.
Post-translational: Phosphorylated upon DNA damage, probably by ATM or ATR. ISGylated.
宿主种属
兔(Rabbit)
特异性
HSPA8
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human Hsc70 (AA 622-636).
阳性对照
WB: Jurkat, HeLa, A549, A431, NIH/3T3 and C6 cell lysates. IHC: Human colon cancer tissue. IF/ICC: MCF7 cells.
偶联
Unconjugated
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 7.4
防腐剂
No
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃(1-2周);长期储存-20℃(12个月);收货后建议分装,避免反复冻融。
图片
Recombinant Hsc70 Antibody (Ab340054) - IHC
Immunohistochemical analysis of paraffin-embedded human colon cancer using Recombinant Hsc70 Antibody (Ab340054).
Recombinant Hsc70 Antibody (Ab340054) - IF/ICC
Immunofluorescent analysis of MCF7 cells using Recombinant Hsc70 Antibody (Ab340054).
Recombinant Hsc70 Antibody (Ab340054) - Western Blot
All lanes: Recombinant Hsc70 Antibody (Ab340054) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution