G protein–coupled receptors (GPCRs) are a large class of cell-surface receptors with a seven-transmembrane architecture and constitute one of the largest membrane receptor families known to date. In the human genome, genes encoding GPCRs account for roughly 4% of all protein-coding genes; among ...
The term "IDG families" likely refers to the Illuminating the Druggable Genome (IDG) project, which is a part of the broader NIH Common Fund's effort to explore and better understand the human genome, specifically focusing on the "druggable" portion of the genome.