Lysosomes are core organelles for cellular catabolism and quality control. They are responsible for degrading materials derived from intracellular autophagy, extracellular endocytosis, phagocytosis, and macropinocytosis. In addition to degradation, lysosomes participate in nutrient sensing, mTOR ...
Metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease (NAFLD), and atherosclerosis, are on the rise globally, posing a significant burden to public health.