Intracellular H₂O₂ and lipid peroxides require the coordinated action of multiple antioxidant enzyme systems for clearance. Among them, Glutathione Peroxidase (GPx), Catalase (CAT), and Peroxiredoxin (PRDX) control peroxides in different substrate and subcellular environments. GPX4 further links ...
The core of selenoprotein research is to clarify how redox reactions involving selenocysteine affect antioxidant defense, mitochondrial homeostasis, inflammatory responses, and cell death. Combined detection of selenoproteins such as GPX, TXNRD, and SELENOP with SOD, CAT, PRDX, GSH/GSSG, ROS, ...
The skin is chronically exposed to multiple oxidative environments, including ultraviolet radiation, air pollution, ozone, visible light, and endogenous metabolic stress. The key to maintaining cutaneous homeostasis does not lie in a single antioxidant ingredient, but in a continuous defense ...