JOURNAL OF MEMBRANE SCIENCE
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2026
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IF 8.8
Zhang-Fu Shi,Peng Cheng,Yi-Fan Li,Jie Yang,Yan Chen,Xiao-Jing Guo,Xi Yan,Wan-Zhong Lang
Polyethylene glycol (PEG), a versatile non-ionic surfactant with excellent biocompatibility and robust chemical stability, offers significant potential for the precise regulation of interfacial polymerization (IP). In this study, PEG was introduced into the aqueous phase as an additive to modulate the interfacial diffusion behavior of piperazine (PIP). By systematically optimizing its molecular weight, concentration, and terminal group parameters, a polyamide (PA) active layer with a smaller and more uniformly distributed pore structure was successfully constructed. This optimized architecture effectively strengthened both the size exclusion and charge repulsion mechanisms of the nanofiltration (NF) membrane. Consequently, the optimal MP 1000 -10 membrane exhibited highly competitive NF performance, achieving an impressive Na 2 SO 4 rejection of 98.0% and a high water permeance of 11.5 L m −2 h −1 bar −1 . More importantly, tailoring the PEG terminal groups facilitated targeted control over the pore size and surface charge properties, significantly enhancing the removal of structurally and physicochemically diverse emerging organic contaminants (EOCs). Across a broad set of experimental parameters, PEG modification consistently delivers improved separation performance for membranes. With excellent stability, high efficiency and economic feasibility, this strategy provides solid technical and theoretical support for developing advanced separation membranes targeting high-efficiency EOCs removal.
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高影响因子
Results in Chemistry
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2026
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IF 5.8
Lei Nie,Ling Wang,Tianxin Wang,Yaling Deng,Wei Guo,Peng Ding
Conductive hydrogels with strong adhesion and antibacterial activity have demonstrated great potential for tissue regeneration applications. In this paper, polypyrrole-doped polydopamine (PDA@PPy) nanocomposites were encapsulated in a polymer hydrogel prepared using quaternary ammonium chitosan (QCS) and aldehyde dextran (ODex), yielding composite hydrogels (QOP). The QOP hydrogels were formed from the pre-solutions within 30 s, and Schiff-base bonds were observed in the polymer network, as verified by Fourier transform infrared (FT-IR) analysis. The fabricated QOP hydrogels displayed a three-dimensional (3D) interconnected porous microstructure, as confirmed by scanning electron microscopy (SEM) and X-ray computed microtomography (Micro-CT) analyses. With increasing PDA@PPy nanocomposite content, the conductivity of QOP hydrogels increased. Furthermore, the QOP hydrogels exhibited good self-healing abilities and strong adhesion to the surfaces of different materials and organs, including rubber, plastic, glass, metal, heart, pancreas, lung, kidney, stomach, liver, and human skin. The −2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid ammonium salt (ABTS) free-radical scavenging rates of over 80% by QOP hydrogels confirmed their excellent antioxidant ability. In addition, the QOP hydrogels demonstrated effective antibacterial activity against the typical bacteria, Escherichia coli ( E. coli, Gram-negative) and Staphylococcus aureus ( S. aureus, Gram-positive). The QOP hydrogels also performed excellent cytocompatibility and good cell migration ability, confirmed using the Cell Counting Kit-8 (CCK-8) approach, fluorescent staining, and cell scratch assay. The available data provide a facile strategy for fabricating a hydrogel bio-adhesive with good antioxidant and potential antibacterial activity for biomedical applications.
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CARBOHYDRATE POLYMERS
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2026
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IF 13.2
Qihui Lin,Zijian Yan,Qiangyu Chen,Yongan Lin,Dan Ying,Zhuhao Tan,Zheng Liu,Mengxing Lu,Wenjing Song,Li Ren
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint destruction, which requires local therapeutic strategies capable of regulating inflammation and cartilage homeostasis. Herein, we report a hyaluronic acid polymer-based core-shell microneedle patch (Mi@PSO/HPA MN) for localized RA treatment with spatially separated payloads and different release profiles. The shell is constructed from crosslinked hyaluronic acid methacrylate (HAMA) and a brush-like hyaluronic acid-based polymer (HPA), while the core is composed of hyaluronic acid (HA) encapsulating psoralen-loaded mPEG-PCL micelles (Mi@PSO). This compartmentalized design integrates the structural advantages of HA-based polymers with potentially complementary therapeutic effects. The outer shell was designed to release HPA earlier, while the core was designed to provide more prolonged Mi@PSO release. In vitro and in vivo results showed that Mi@PSO/HPA MNs reduced inflammatory marker expression, modulated macrophage polarization-related markers toward an anti-inflammatory profile, preserved cartilage matrix-related markers, and alleviated joint damage in CIA mice under the tested treatment regimen. Overall, this work presents a hyaluronic acid-based polymer-engineered core-shell microneedle platform that combines minimally invasive administration, staged local delivery, inflammation control, and cartilage protection, offering a promising strategy for RA management.
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SENSORS AND ACTUATORS B-CHEMICAL
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2026
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IF 8.3
Zehui Wei,Yukai He,Shuxian Ge,Lina Mu,Shuangxian Yan,Kefan Xie,Tiantian Gao,Miaomiao Zhang,Jilei Yin,Mei Tian
Saxitoxin (STX), a typical paralytic shellfish toxin, poses a serious threat to seafood safety and public health. Meanwhile, valganciclovir hydrochloride (VAL), a commonly prescribed antiviral agent, requires rigorous therapeutic drug monitoring. To overcome the limitations of current methods reliant on costly instrumentation and complex procedures, this study developed a dual-functional fluorescent probe for rapid quantification of STX and VAL via a dummy-template imprinting strategy. Using VAL as both the imprinting template and the pseudo-template for STX, 2-acrylamido-2-methylpropanesulfonic acid and sodium methallylsulfonate as functional monomers, and trimethylolpropane trimethacrylate as crosslinking agent, a highly hydrophilic molecularly imprinted polymer (MIP) was synthesized. The fluorescent probe was subsequently constructed by adsorbing rhodamine 6 G (Rh6G), enabling specific recognition and sensitive detection of both targets. The probe showed good linearity and detection performance toward STX (2–200 ng/mL, LOD: 0.84 ng/mL) and VAL (12.5–700 ng/mL, LOD: 3.70 ng/mL), along with satisfactory reproducibility (RSD ≤ 4.6%, n = 6) and stability. The imprinting factor for STX reached 4.07, and the selectivity factors against domoic acid and pectenotoxin-2 were 3.37 and 2.97, respectively. The probe was applied to quantify STX in clams and seawater samples, and VAL in mouse serum and rat plasma, yielding recoveries of 86.0%–91.4%, 82.9%–89.0%, 91.5%–97.3%, and 85.0%–91.7%, respectively. This study demonstrates the dual-functional recognition and sensitive detection capability of pseudo-template imprinting fluorescent probes, providing useful references for the rapid screening of marine biotoxins and antiviral drugs in biological matrices.
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JOURNAL OF IMMUNOLOGICAL METHODS
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2026
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IF 1.7
Jiayue Song,Li Wang,Qin Zhang,Haili Wang,Xiao Liu,Jingming Zhou,Aiping Wang
Pseudorabies virus (PRV) remains a major threat to the global swine industry, and the development of rapid, sensitive, and reliable diagnostic methods is critical for effective disease control. In this study, we developed and validated a quantum dot-based fluorescent immunochromatographic strip assay (QDs-FICS) for the rapid detection of PRV glycoprotein B (gB). Recombinant PRV gB protein was expressed in HEK293F cells and used as the immunogen to generate monoclonal antibodies. An optimal antibody pair was screened using a double-antibody sandwich ELISA and subsequently employed to construct the fluorescent immunochromatographic assay. The performance of the assay was systematically evaluated in terms of specificity, sensitivity, and stability. Qualitative spike-in validation in PRV-negative porcine serum was further performed to verify its practical applicability in clinical samples. The results demonstrated that the QDs-FICS exhibited high specificity without cross-reactivity to other viral proteins, high sensitivity with a visual limit of detection of 10 2.5 TCID 50 /100 μL, and satisfactory stability during storage. Moreover, the assay could be completed within a short time and required minimal operational procedures. Collectively, the QDs-based fluorescent immunochromatographic assay established in this study provides a rapid, sensitive, and reliable tool for PRV antigen detection, and has strong potential for application in clinical diagnosis, epidemiological surveillance, and on-site detection of pseudorabies.
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Sensing and Bio-Sensing Research
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2026
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IF 4.7
Ahmad Movahedpour,Omid Sheydaei,Arash Asfaram,Sajedeh Karami,Hassan Ghasemi
This study presents the design and electrochemical characterization of a highly sensitive and selective sensor for the determination of D−/L- kynurenine (D−/L- KYN), based on a carbon paste electrode (CPE) modified with multi-walled carbon nanotubes (MWCNTs). The electrocatalytic oxidation of D−/L-KYN at the MWCNT-modified CPE was systematically investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The Structural and morphological characteristics of the MWCNTs were characterized by Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD). The combined characterization results confirmed the successful functionalization, morphological integrity, and crystalline structure of the MWCNTs, supporting their suitability as an efficient electrode modifier. At physiological pH (7.0) in phosphate buffer solution (PBS), D−/L-KYN exhibited a well-defined oxidation peak at +0.85 V (vs. Ag/AgCl). The electrochemical behavior of the analyte followed a diffusion-controlled mechanism involving a two-electron/two-proton transfer process. Key analytical parameters including solution pH and scan rate were optimized to enhance sensor performance. The fabricated sensor exhibited a linear concentration range of 0.06–40.0 μM, with an impressive limit of detection 3 nM (S/N = 3). Furthermore, the sensor demonstrated excellent reproducibility and repeatability, with relative standard deviations (RSDs) of 3.8% and 3.3%, respectively. The developed platform was successfully applied to the quantification of D−/L-KYN in spiked human plasma samples, demonstrating its potential for clinical and biomedical applications.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
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IF 9.6
Yeshun Tian,Hao Liu,Changliang Wu,Xiao Xia,Guangbin Duan,Zongming Liu
MoO 4 2− triggers rapid reconstruction of NiFe into corrosion-resistant LDH. • Surface MoO 4 2− stabilizes Fe, promotes high-valence Ni; detached ions sieve Cl − . • Delivers 1000 h durability at 500 mA cm −2 in natural seawater with 4.65 kW⸳h/Nm 3 H 2 . Suppressing the chlorine evolution reaction and mitigating chloride-induced corrosion remain central challenges for seawater electrolysis. Herein, this paper proposes an anion-accelerated directional catalyst reconstruction strategy. Guided by density functional theory (DFT) screening among a series of oxyanions, MoO 4 2− is identified as the optimal species to tailor the NiFe surface. MoO 4 2− not only drives the rapid and controlled reconstruction of NiFe into highly corrosion-resistant NiFe layered double hydroxide (LDH) but also optimizes the surface electronic structure, thereby lowering the oxygen evolution reaction (OER) energy barrier and enhancing intrinsic activity. The resulting MoO 4 2− /NiFe LDH delivers an overpotential of only 324.85 mV at 100 mA·cm −2 and exhibits extraordinary durability in natural seawater, operating stably at 500 mA·cm −2 for over 1000 h. Mechanistic investigations reveal a dual protection mechanism: surface-anchored MoO 4 2− stabilizes Fe sites while promoting the formation of high-valence Ni active species, and detached MoO 4 2− confined within the electric double layer functions as an ion sieve, selectively repelling Cl − and reinforcing corrosion resistance. When integrated with commercial platinum on carbon (Pt/C) in an anion exchange membrane (AEM) electrolyzer, the system achieves a cell voltage of only 1.96 V at 500 mA·cm −2 , stable operation for 200 h, and a remarkably low energy consumption of 4.65 kW·h/Nm 3 H 2 , outperforming conventional RuO 2 -based systems. The paradigm of anion-accelerated reconstruction is established, endowing earth abundant catalysts with excellent seawater corrosion resistance and bringing practical industrial scale hydrogen production from seawater electrolysis one step closer. Download: Download high-res image (159KB) Download: Download full-size image
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PubMed
高影响因子
ELECTROCHIMICA ACTA
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2026
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IF 5.8
Sa Xue,Yukun Zhang,Xiangyang Liu,Maogang He
Both TFETFE and 2FB enhance Li⁺-anion interaction, increasing AGGs contents. • 2FB promotes Li⁺-anion interaction more effectively than TFETFE, forming more AGGs. • Inorganic-rich SEI and CEI are generated by deep decomposition of anions in PPB. • Li|PPB|LFP full battery displays a capacity retention of 83.6% after 150 cycles. Due to the low viscosity and weak polarity, fluorinated ethers and fluorinated aromatic compounds are widely used as fluorinated diluents in locally concentrated ionic liquid electrolytes (LCILEs) to improve the electrochemical performance of ionic liquid electrolytes (ILEs). However, the extent to which these two types of diluents regulate Li + solvation structure remains unclear. In this work, two LCILEs were designed using 1,1,2,2-tetrafluoroethyl 2,2,2-trifluoroethyl ether (TFETFE) and 1,2-difluorobenzene (2FB) as diluents, denoted as PPT and PPB, respectively. Raman spectroscopy reveals that both TFETFE and 2FB can strengthen the interaction between Li⁺ and anion, thereby promoting the formation of aggregate ion pairs (AGGs). Compared with TFETFE, 2FB exhibits a more pronounced ability to enhance Li⁺-anion interaction, increasing the proportion of AGGs in PPB electrolyte to 42%, which is significantly higher than that in PPT electrolyte (30%). The enriched AGGs facilitates the preferential reduction and deep decomposition of FSI⁻ at the electrode/electrolyte interphase, leading to the formation of inorganic-rich (LiF, Li 3 N, Li 2 S and Li 2 O) solid electrolyte interphase (SEI) and cathode electrolyte interphase (CEI) with the compact and uniform morphologies. Benefiting from the favorable interfacial chemistry, Li||Cu half battery based on PPB electrolyte delivers a high Li plating/stripping Coulombic efficiency (CE) of 98.7% at 1 mA·cm -2 , exceeding that of PPT (98.0%). In addition, the Li||Li symmetric battery exhibits stable cycling for 160 hours at 2 mA·cm -2 . The Li|PPB|LFP full battery further retains 83.6% of its initial capacity after 150 cycles with an average CE of 99.8%, demonstrating superior electrochemical performance. This work provides practical guidance for the rational selection and structural design of diluents for high performance lithium metal battery electrolytes. Download: Download high-res image (231KB) Download: Download full-size image
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SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Zhongmin Feng,Zheng Wang,Li-hua Qi,Sijie Yun,Chuang Zu,Ling Huang,Shengping Wang,Huanting Wang
Gas separation using metal organic framework (MOF) membranes has attracted considerable attention in recent years. Despite the progress made, establishing thin, defect-free MOF layers within the porous polymer remains a significant challenge. In this study, a novel approach is reported for the preparation of ZIF-8/Polyethersulfone (ZIF-8/PES) composite membranes via non-solvent-induced phase separation (NIPS)-triggered in-situ crystallization strategy. In this method, PES serves as a solid solvent for Zn(NO 3 ) 2 . During the NIPS process, an asymmetric PES membrane with a skin layer, finger-like pores, and interconnected foam structures is formed. Concurrently, Zn(NO 3 ) 2 diffuses to the skin layer and reacts with 2-methylimidazole (2-MIM), yielding a dense ZIF-8 layer on the PES surface. The simultaneous nucleation and growth of ZIF-8 within the polymer create strong interfacial interactions at the organic-inorganic interface. These interactions improve the compatibility between ZIF-8 and the polymer matrix, reduce interfacial defects. As a result, the composite membrane exhibits enhanced mechanical stability. When the crystallization time is extended to 48 h, the thickness of the ZIF-8 layer reaches approximately 540 nm, and the membrane exhibits an H 2 /CO 2 selectivity of 72.3 ± 3.35 at 298 K. This study provides a facile and effective route for constructing thin MOF membranes on polymeric matrix for high-performance gas separation.
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高影响因子
Journal of Cleaner Production
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2026
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IF 10.7
Min Zhou,Ningbo Yu,Dongyang Li,Minghao Wang,Hongxia Gao,Zhiwu Liang
Intrinsic CO 2 kinetics of cyclic amines are quantified in water-lean ethers. • Zwitterion mechanism is validated as dominant in aprotic ether-water mixtures. • Ether solvents impede CO 2 absorption by disrupting the dynamic H-bond network. • MD shows an ether-induced solvent cage effect restricting CO 2 access to amines. • Rigid C-substituted amines with high nucleophilicity suit ether-based systems. Piperazine-derived cyclic amines represent promising solutions for efficient CO 2 capture. However, fundamental understanding of their structure-activity relationships remains limited. This work combined experimental and computational approaches to elucidate the influences of cyclic structures and functional groups of piperazine-derived cyclic amines (PZ, 2MPZ, AEP, 1MPZ and 2HPZ) on their CO 2 capture performance and the structure-activity relationship in both pure water and water-lean environments. Key findings reveal that substituents reduce nitrogen electron density and impose steric hindrance, impeding CO 2 access to active sites. Stopped-flow measurements of the intrinsic kinetics of cyclic amines in aqueous and ether-water solvents revealed a reactivity trend: PZ > 2MPZ > AEP > 1MPZ > 2HPZ. The zwitterion mechanism demonstrates relatively good accuracy (AARD: 1.30%-2.66%) than base-catalyzed hydration (AARD: 2.62%-9.46%). DFT validates the zwitterion pathway, while MD simulations indicate that pure water solution maintains dynamic hydrogen-bond networks without outer-layer clustering. Ether addition disrupts hydrogen bonding and diminishes electron density at reactive sites, reducing absorption rates. These findings elucidate the underlying structure-activity relationships and solvation effects, providing a fundamental molecular-level understanding of the kinetic behaviors in water-lean amine systems. Download: Download high-res image (578KB) Download: Download full-size image
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INDUSTRIAL CROPS AND PRODUCTS
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2026
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IF 6.4
Chunping Wang,Qi Zhang,Yan Lu,Tong Liu,Le Wang,Yuhan Li,Siyu Zhao,Bin Li,Lili Fu,Yangbing Wen
Cellulose nanofibers effectively stabilized the aqueous boron nitride dispersion. • BN thermally conductive network was constructed within the substrate. • The BN thermally conductive network significantly boosts raw material pyrolysis. • The thermally conductive network can reduce residual glycerin by 29.32%. • The thermally conductive network can reduce residual nicotine by 74.24%. Traditional paper-based materials suffer from low heat transfer efficiency, severely limiting the uniform and efficient generation of aerosols in heated tobacco products (HTPs). This study utilized cellulose nanofibers (CNFs) to surface-activate highly thermally conductive hexagonal boron nitride (BN) and uniformly dispersed it in a paper-based reconstituted tobacco (RT) substrate, successfully constructing a continuous heat transfer network. The composite substrate exhibits excellent out-of-plane thermal conductivity (0.1559 W/(m·K)) and an extremely fast transient thermal response rate (13 °C/s). Distributed activation energy model (DAEM) kinetics further confirmed that this optimized thermal conductivity architecture significantly reduces the apparent mass-loss activation energy during the thermal conversion process. Mass spectrometry results showed that, compared to the control group, the relative EIC peak areas (reflecting the relative release intensities) of glycerol and nicotine increased to 134.50 ± 0.68% and 158.38 ± 0.25%, respectively. More importantly, it achieved exceptionally good puff-by-puff release consistency, reducing the coefficients of variation (CV) of glycerol and nicotine release to 13.7 ± 0.39% and 21.11 ± 0.65%, respectively. Crucially, this work demonstrates a high-value industrial application of crop-derived nanocellulose, highlighting its tremendous potential in engineering advanced, bio-based functional composites for thermal management. Download: Download high-res image (276KB) Download: Download full-size image
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SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Xiaoyuan Zhang,Rui Zeng,Zhenbei Wang,Fei Qi,Chen Li,Yatao Liu,Fan Li,Ziteng Chen,Yujia Yuan,Zhuoran Bai,Yongshun Yu,Jun Nan,Amir Ikhlaq,Shengnan Li
The potential of Fe(VI) enhanced coagulation-ultrafiltration (C-UF) for the simultaneous enhancement of ibuprofen (IBP) removal and membrane alleviation was investigated by comparing Fe(VI)-UF, FeCl 3 -UF, AlCl 3 -UF, Fe(VI)-FeCl 3 -UF, and Fe(VI)-AlCl 3 -UF. The results showed that Fe(VI)-FeCl 3 -UF and Fe(VI)-AlCl 3 -UF achieved IBP removal efficiencies of 66.6% and 76.9%, respectively, which were significantly higher than those obtained with Fe(VI)-UF, FeCl 3 -UF, AlCl 3 -UF. This confirmed that Fe(VI) enhanced C-UF could effectively improve IBP removal compared to individual Fe(VI)-UF or conventional C-UF. This improvement was attributed to additional highly reactive Fe(V)/Fe(IV) intermediates generated by adding metal coagulants to instantaneously activate residual Fe(VI) during the Fe(VI) enhanced C-UF process. In addition, Fe(VI)-FeCl 3 -UF and Fe(VI)-AlCl 3 -UF further alleviated total membrane fouling compared to FeCl 3 -UF and AlCl 3 -UF, with a significant shift of membrane fouling toward reversible fouling. Floc properties, NOM characteristics, and membrane surface characterization were comprehensively analyzed to reveal membrane fouling alleviation mechanisms in Fe(VI) enhanced C-UF. Simultaneous cleavage into smaller molecules and polymerization into larger fractions of NOM by Fe(VI) could reduce the affinity of foulants for membrane surface adsorption and consequently lower irreversible fouling. While Fe(VI) reduction would produce iron-based hydroxides to participate in the growth process of flocs, leading to the formation of flocs with higher density. These flocs would accumulate on membrane surface to form a denser cake layer, which contributed to severe membrane fouling.
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危险品化学品经营许可证（带存储）