Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 μg/ml, corresponding to a specific activity of > 2500 IU/mg in the presence of 15 ng/ml of rHuIGF-II.
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
规格
产品名称
Recombinant Human IGFBP5 Protein
别名
重组人IGFBP5蛋白 | 重组人 IGFBP5 蛋白
英文别名
IBP5IBP-5 | IGF-binding protein 5 | IGFBP5 | IGFBP-5 | Insulin-like growth factor binding protein 5 | Insulin-like growth factor-binding protein 5 | IBP 5 | IBP-5 | IBP5 | IBP5_HUMAN | IGF binding protein 5 | IGF BP5 | IBP-5 | IGF-binding protein 5 | IGFB
Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 μg/ml, corresponding to a specific activity of > 2500 IU/mg in the presence of 15 ng/ml of rHuIGF-II.
Lyophilized from a 0.2 μm filtered concentrated solution in 10 mM Sodium Citrate, pH 3.0
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Recombinant Human IGFBP5 Protein (rp147287)-Protein Bioactivity Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 μg/mL, corresponding to a specific activity of > 2500 IU/mg in the presence of 15 ng/mL of rHuIGF-II.
Recombinant Human IGFBP5 Protein (rp147287)-SDS-PAGE Recombinant Human IGFBP5 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 28.6 kDa.
ZJ23F0600314
危险品化学品经营许可证（带存储）