Measured by its ability to inhibit the IL-18-induced response of KG‑1 human acute myelogenous leukemia cells in the presence of Recombinant Human IL‑18 R alpha /IL‑1 R5. The ED50 for this effect is 2‑6 µg/mL.
Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.
规格
产品名称
Recombinant Human IL-18 R beta/IL-1 R7 Protein
别名
重组人IL-18 R beta蛋白 | 重组人白细胞介素-18受体Beta链蛋白 | 重组人IL-1 R7蛋白 | 重组人 IL-18 R beta/IL-1 R7 蛋白
Measured by its ability to inhibit the IL-18-induced response of KG‑1 human acute myelogenous leukemia cells in the presence of Recombinant Human IL‑18 R alpha /IL‑1 R5. The ED50 for this effect is 2‑6 µg/mL.
50 - 60 kDa, under reducing conditions; 47 - 57 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human IL-18 R beta/IL-1 R7 Protein (rp147453) - Protein Bioactivity Measured by its ability to inhibit the IL-18-induced response of KG‑1 human acute myelogenous leukemia cells in the presence of Recombinant Human IL-18 R beta/IL-1 R7 Protein (rp147453) .The ED50 for this effect is 3.30 µg/mL.
Recombinant Human IL-18 R beta/IL-1 R7 Protein (rp147453) - SDS-PAGE 3 μg/lane of Recombinant Human IL-18 R beta/IL-1 R7 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 50 - 60 kDa under reducing condition and 47 - 57 kDa under non-reducing condition.