Purity ≥95% SDS-PAGE. Endotoxin level <0.1 EU/µg Function Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
90 - 110 kDa, under reducing conditions; 200 - 200 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human IL-23R Protein (rp147522) - Protein Bioactivity Immobilized Human IL- 12B&IL-23A Protein at 5.0 μg/mL can bind Recombinant Human IL-23R Protein (rp147522) with the ED50 is 128.2 ng/mL.
Recombinant Human IL-23R Protein (rp147522) - SDS-PAGE 3 μg/lane of Recombinant Human IL-23R Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 90 - 110 kDa under reducing condition and 200 - 220 kDa under non-reducing condition.