Measured by its binding ability in a functional ELISA. When Recombinant Human IFN-alpha / beta R1 is present at 10 μg/mL, it binds to Recombinant Human IFN‑ alpha / beta R2 Fc Chimera in the presence of recombinant human IFN-alpha 2. The concentration of Recombinant Human IFN-alpha / beta R2 Fc Chimera that produces 50% of the optimal binding response is approximately 0.5-1.5 μg/mL.
Purity ≥95% SDS-PAGE. Endotoxin level <0.1 EU/µg Function Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.
规格
产品名称
Recombinant Human IFN-alpha/beta R1 Protein
别名
重组人IFN-alpha/beta R1蛋白 | 重组人干扰素α/β受体蛋白
英文别名
alpha-type antiviral protein | AVP | beta-type antiviral protein | CRF2-1 | Cytokine receptor class-II member 1 | Cytokine receptor family 2 member 1 | human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC | IFN-alpha/beta R1 | IFN-alpha/beta receptor 1
Measured by its binding ability in a functional ELISA. When Recombinant Human IFN-alpha / beta R1 is present at 10 μg/mL, it binds to Recombinant Human IFN‑ alpha / beta R2 Fc Chimera in the presence of recombinant human IFN-alpha 2. The concentration of Recombinant Human IFN-alpha / beta R2 Fc Chimera that produces 50% of the optimal binding response is approximately 0.5-1.5 μg/mL.
Lyophilized from 10mM PBS, 5% trehalose, 5% mannitol, pH7.4.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。复溶后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human IFN-alpha/beta R1 Protein (rp147754) - SDS-PAGE 2 μg/lane of Recombinant Human IFN-alpha/beta R1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 65 - 85 kDa.