26 kDa cell surface protein TAPA 1 | 26 kDa cell surface protein TAPA-1 | 26 kDa cell surface protein TAPA1 | CD 81 | CD81 | CD81 antigen | CD81 antigen (target of antiproliferative antibody 1) | CD81 molecule | CD81_HUMAN | CVID6 | S5.7 | TAPA 1 | TAPA1
规格或纯度
无动物源,无载体,His标签,PBS Only,≥95%(SDS-PAGE),见COA
生化机理
CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.
Post-translational: Not glycosylated. Likely constitutively palmitoylated at low levels. Protein palmitoylation is up-regulated upon coligation of BCR and CD9-C2R-CD81 complexes in lipid rafts.
10.0 kDa, under reducing conditions; 10.2 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4.
浓度
见COA
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃保存 12个月；复溶后建议分装，避免反复冻融。
图片
Recombinant Human CD81 Protein (rp181595) - SDS-PAGE 3 μg/lane of Recombinant Human CD81 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 10.0 kDa under reducing conditions and 10.2 kDa under non-reducing conditions.
ZJ25F0826005
危险品化学品经营许可证（带存储）