DEFB118 is a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This protein is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Recombinant human DEFB118 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Post-translational: The three-dimensional structure formed by the three intramolecular disulfide bridges is indispensable for antimicrobial activity.
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
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Recombinant Human DEFB118 Protein (rp189382) - SDS-PAGE 3 μg/lane of Recombinant Human DEFB118 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 14.7 kDa under reducing conditions and 15.1 & 30.7 kDa under non-reducing conditions.
ZJ25F0116430
危险品化学品经营许可证（带存储）