Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
生物活性
Immobilized Recombinant Human IFN-alpha-1a Protein (rp222551) at 1.0 μg/mL can bind Rontalizumab (anti-IFNA1) (Ab175647) with the EC50 of 60.2 ng/mL.
18.3 kDa, under reducing conditions; 16.8 & 33.1 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4.
浓度
见COA
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.1 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20℃ for 6 months. Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Human IFN-alpha-1a Protein (rp222551) - ELISA Immobilized Recombinant Human IFN-alpha-1a Protein (rp222551) at 1.0 μg/mL can bind Rontalizumab (anti-IFNA1) (Ab175647) with the EC₅₀ of 60.2 ng/mL.
Recombinant Human IFN-alpha-1a Protein (rp222551) - SDS-PAGE 3 μg/lane of Recombinant Human IFN-alpha-1a Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 18.3 kDa under reducing conditions and 16.8 & 33.1 kDa under non-reducing conditions. The observation of protein as both dimers and monomers under non-reducing (NR) conditions suggests that a portion of the protein forms dimers. This dimerization may be mediated by (or stabilized by) disulfide bonds (Uniprot: P01562).