ExactAb™,已验证,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human C4d Antibody, Recombinant (MyR1-C4d), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Protein Function
C4 plays a central role in the activation of the classical pathway of the complement system. It is processed by activated C1 which removes from the alpha chain the C4a anaphylatoxin. The remaining alpha chain fragment C4b is the major activation product and is an essential subunit of the C3 convertase (C4b2a) and the C5 convertase (C3bC4b2a) enzymes of the classical complement pathway.
Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Recombinant C4d Antibody (Ab092216) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling C4d with Recombinant C4d Antibody (Ab092216) at 1/100 dilution. The section was incubated with Ab092216 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.
1/100 - 1/200
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