Rabbit anti Human Factor H Antibody, Recombinant, could be used for WB and so on.
规格
产品名称
Recombinant Factor H Antibody
别名
Factor H抗体 | Factor H重组抗体 | 补体因子H抗体
英文别名
adrenomedullin binding protein antibody | age related maculopathy susceptibility 1 antibody | AHUS 1 antibody | AHUS1 antibody | AMBP 1 antibody | AMBP1 antibody | ARMD 4 antibody | ARMD4 antibody | ARMS 1 antibody | ARMS1 antibody | beta 1 H globulin ant
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
Glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. For example, interacts with CR3/ITGAM receptor and thereby mediates the adhesion of human neutrophils to different pathogens. In turn, these pathogens are phagocytosed and destroyed. (Microbial infection) In the mosquito midgut, binds to the surface of parasite P.falciparum gametocytes and protects the parasite from alternative complement pathway-mediated elimination.
宿主种属
兔(Rabbit)
特异性
Factor H
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human Factor H (AA 150-200).
Recombinant Factor H Antibody (Ab102656) - Western Blot All lanes: Recombinant Factor H Antibody (Ab102656) at 1/2000 dilution Samples: Lysates at 20 µL (1/300 dilution) per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 139 kDa Observed band size: 168 kDa Exposure time: 31.4 s
ZJ25F0217734
危险品化学品经营许可证（带存储）