去甲二氢愈创木酸

货号 (SKU)	包装规格	是否现货
N133726-250mg	250mg	现货
N133726-1g	1g	现货
N133726-5g	5g	现货

基本描述

别名	NDGA\|马索罗酚\|1,4-双(3,4-二羟苯基)-2,3-二甲基丁烷, 4,4'-(2,3-二甲基四亚甲基)二邻苯二酚
英文别名	NORDIHYDROGUAIARETIC ACID\|500-38-9\|NDGA\|Dihydronorguaiaretic acid\|Actinex\|4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol\|Norhydroguaiaretic acid\|Norguaiaretic acid, dihydro-\|1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-\|Dinorguaia
规格或纯度	≥95%
英文名称	Nordihydroguaiaretic Acid
生化机理	脂氧合酶抑制剂；含多酚的邻二羟基（儿茶酚）结构。天然有效的抗氧化剂。体内外多种药理作用。抗癌，抗微生物，抗炎和免疫抑制活性。
储存温度	2-8°C储存
运输条件	冰袋运输
备注	如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍	产品介绍 Nordihydroguaiaretic acid (NDGA) is used as an antioxidant and potent scavenger of reactive oxygen species (ROS) 用途 Nordihydroguaiaretic acid can be used: In the synthesis of nordihydroguaiaretic acid derivatives with potent HIV inhibition activity；As a starting material in the synthesis of tetra-O-methylnordihydroguaiaretic acid. Product Introduction Nordihydroguaiaretic acid (NDGA) is used as an antioxidant and potent scavenger of reactive oxygen species (ROS) Application Nordihydroguaiaretic acid can be used: In the synthesis of nordihydroguaiaretic acid derivatives with potent HIV inhibition activity；As a starting material in the synthesis of tetra-O-methylnordihydroguaiaretic acid.

名称和标识符

IUPAC Name	4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
INCHI	InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
InChi Key	HCZKYJDFEPMADG-UHFFFAOYSA-N
Canonical SMILES	CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
Isomeric SMILES	CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
WGK Germany	3
RTECS	UX1750000
PubChem CID	4534
分子量	302.37
Beilstein号	6(1)577
Reaxy-Rn	9803564

数据库链接

DrugBank Ligand	DB00179
Wikipedia	Nordihydroguaiaretic_acid, Masoprocol
CAS Registry No.	500-38-9
PubChem CID	4534
ChEMBL Ligand	CHEMBL52

化学和物理性质

溶解性	Soluble in 100% ethanol, methanol, acetone, dimethylsulfoxide, dimethylformamide, ethanol (5% w/v), glycol, PEG, and slightly soluble in hot water. Insoluble in water.
熔点	184-188℃

安全和危险性（GHS）

象形图	Harmful
信号词	Warning
危险声明	H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H302: Harmful if swallowed
预防措施声明	P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319
WGK Germany	3
RTECS	UX1750000
Reaxy-Rn	9803564
Merck Index	6693
个人防护装备	dust mask type N95 (US)， Eyeshields， Gloves

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参考文献

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