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脱氧胆酸钠

水溶性离子去污剂,用于溶解膜结合蛋白。
规格或纯度: 10mM in DMSO
有货

库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
S423127-1ml
1ml 现货 Stock Image

基本描述

别名 去氧胆酸钠
英文别名 Sodium deoxycholate|Deoxycholic acid sodium salt|302-95-4|Sodium desoxycholate|Deoxycholate sodium|Desoxycholate sodium|Sodium 7-deoxycholate|Sodium deoxycholic acid|Deoxycholic acid, sodium salt|CHEBI:9177|DTXSID5033389|436LS6U35Y|Kybella|NCGC00091038-01
规格或纯度 10mM in DMSO
英文名称 Sodium deoxycholate
生化机理 增加脂肪的溶解,以促进其在肠中的吸收.水溶性离子去污剂,用于提取膜受体和其他质膜蛋白。据报道可诱导β-catenin的酪氨酸磷酸化并随后转移至细胞核,促进β-catenin信号的激活
储存温度 -80℃储存
运输条件 超低温冰袋运输
产品介绍

Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins. Deoxycholic Acid, Sodium Salt is reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 μM). 脱氧胆酸钠是一种胆盐和离子型去污剂。胆盐在肠中可与脂质/脂肪/胆固醇作用并形成混合的胶束。这些胶束可帮助脂肪的消化以及通过肠壁的吸收

Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins. Deoxycholic Acid, Sodium Salt is reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 μM). Sodium deoxycholate is a bile salt and an ionic detergent. Bile salts work along with lipids/fats/cholesterol and form mixed micelles in the intestine. These micelles help in fat digestion and absorption through the intestinal wall
An ionic detergent for the solubilization of membrane-bound proteins.

名称和标识符

EC号 206-132-7
IUPAC Name sodium;(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
INCHI InChI=1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
InChi Key FHHPUSMSKHSNKW-SMOYURAASA-M
Canonical SMILES CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
Isomeric SMILES C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]
WGK Germany 3
RTECS FZ2250000
PubChem CID 23668196
分子量 414.56
Beilstein号 3581950

化学和物理性质

敏感性 易吸潮
比旋光度 42° (C=2,H2O)

安全和危险性(GHS)

象形图
ghs07

Harmful

信号词 Warning
危险声明 H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H302: Harmful if swallowed
预防措施声明 P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319
WGK Germany 3
RTECS FZ2250000
个人防护装备 dust mask type N95 (US),Eyeshields,Gloves

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