脱氧胆酸钠
库存信息
货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
---|---|---|---|---|
S423127-1ml |
1ml | 现货 | |
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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
---|---|---|---|---|
S423127-1ml |
1ml | 现货 | |
别名 | 去氧胆酸钠 |
---|---|
英文别名 | Sodium deoxycholate|Deoxycholic acid sodium salt|302-95-4|Sodium desoxycholate|Deoxycholate sodium|Desoxycholate sodium|Sodium 7-deoxycholate|Sodium deoxycholic acid|Deoxycholic acid, sodium salt|CHEBI:9177|DTXSID5033389|436LS6U35Y|Kybella|NCGC00091038-01 |
规格或纯度 | 10mM in DMSO |
英文名称 | Sodium deoxycholate |
生化机理 | 增加脂肪的溶解,以促进其在肠中的吸收.水溶性离子去污剂,用于提取膜受体和其他质膜蛋白。据报道可诱导β-catenin的酪氨酸磷酸化并随后转移至细胞核,促进β-catenin信号的激活 |
储存温度 | -80℃储存 |
运输条件 | 超低温冰袋运输 |
产品介绍 |
Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins. Deoxycholic Acid, Sodium Salt is reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 μM). 脱氧胆酸钠是一种胆盐和离子型去污剂。胆盐在肠中可与脂质/脂肪/胆固醇作用并形成混合的胶束。这些胶束可帮助脂肪的消化以及通过肠壁的吸收 Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins. Deoxycholic Acid, Sodium Salt is reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 μM). Sodium deoxycholate is a bile salt and an ionic detergent. Bile salts work along with lipids/fats/cholesterol and form mixed micelles in the intestine. These micelles help in fat digestion and absorption through the intestinal wall |
EC号 | 206-132-7 |
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IUPAC Name | sodium;(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate |
INCHI | InChI=1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1 |
InChi Key | FHHPUSMSKHSNKW-SMOYURAASA-M |
Canonical SMILES | CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+] |
Isomeric SMILES | C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+] |
WGK Germany | 3 |
RTECS | FZ2250000 |
PubChem CID | 23668196 |
分子量 | 414.56 |
Beilstein号 | 3581950 |
敏感性 | 易吸潮 |
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比旋光度 | 42° (C=2,H2O) |
象形图 |
Harmful |
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信号词 | Warning |
危险声明 |
H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H302: Harmful if swallowed |
预防措施声明 | P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319 |
WGK Germany | 3 |
RTECS | FZ2250000 |
个人防护装备 | dust mask type N95 (US),Eyeshields,Gloves |
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