Rabbit anti Human AIMP2/p38 Antibody, Polyclonal, could be used for WB, IHC and so on. Application: WB: 1/500-1/1000 IHC: 1/50-1/100 Protein Function: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
规格
产品名称
AIMP2/p38 Antibody
别名
AIMP2/p38抗体
英文别名
AIMP2_HUMAN antibody | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 antibody | Aminoacyl tRNA synthetase complex interacting multifunctional protein 2antibody | ARS interacting multi functional protein 2antibody | JTV 1 antibody |
规格或纯度
ExactAb™, Validated, Carrier Free, 0.1 mg/mL
宿主种属
兔(Rabbit)
特异性
AIMP2/p38
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human AIMP2/p38 (AA 37-69).
阳性对照
WB: HeLa, A549 and NIH/3T3 cell lysates. IHC: Human cervical cancer tissue. IF/ICC: HeLa cells.
AIMP2/p38 Antibody (Ab087798) - Western Blot All lanes: AIMP2/p38 Antibody (Ab087798) at 1/500 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution Predicted band size: 35 kDa Observed band size: 36 kDa Exposure time: 100.0 s
AIMP2/p38 Antibody (Ab087798) - IHC Immunohistochemistry analysis of paraffin-embedded Human cervical cancer using AIMP2/p38 Antibody (Ab087798). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
AIMP2/p38 Antibody (Ab087798) - IF/ICC IF analysis of AIMP2/p38 Antibody (Ab087798) in HeLa cells. The cells were fixed and permeabilized with 100% methanol for 5 minutes, and blocked with 5% BSA for 1 hour at room temperature. Cells were stained with AIMP2/p38 Antibody (Ab087798) at 1/200 dilution in blocking buffer overnight at 4°C, and then incubated with Goat Anti-Rabbit IgG H&L (AF488) (Ab181954) at a dilution of 1/1000 for 1 hour at room temperature in the dark (green). Cells were counterstained with DAPI (blue).