Aldolase B: Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde. Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check.
宿主种属
兔(Rabbit)
特异性
Aldolase B/C
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human Aldolase C (AA 90-150).
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Aldolase B/C Antibody (Ab088115) - Western Blot All lanes: Recombinant Aldolase B/C Antibody (Ab088115) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 39 kDa Observed band size: 39 kDa Exposure time: 15.8 s
Recombinant Aldolase B/C Antibody (Ab088115) - Western Blot All lanes: Recombinant Aldolase B/C Antibody (Ab088115) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 39 kDa Observed band size: 39 kDa Exposure time: 15.8 s
ZJ25F0218722
危险品化学品经营许可证（带存储）