Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
宿主种属
兔(Rabbit)
特异性
alpha 1 Antitrypsin
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human alpha 1 Antitrypsin (AA 1-418)
Recombinant alpha 1 Antitrypsin Antibody (Ab088239) - Western Blot All lanes: Recombinant alpha 1 Antitrypsin Antibody (Ab088239) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 47 kDa Observed band size: 53, 59 kDa Recombinant alpha 1 Antitrypsin Antibody (Ab088239) recognizes two isoforms of alpha 1 Antitrypsin. Exposure time: 12.9 s
Recombinant alpha 1 Antitrypsin Antibody (Ab088239) - Western Blot All lanes: Recombinant alpha 1 Antitrypsin Antibody (Ab088239) at 1/1000 dilution Samples: Lysates at 10 µL (1/300 dilution) per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 47 kDa Observed band size: 48, 54 kDa Recombinant alpha 1 Antitrypsin Antibody (Ab088239) recognizes two isoforms of alpha 1 Antitrypsin. Exposure time: 7.6 s
ZJ24F1215670
危险品化学品经营许可证（带存储）