Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues.
宿主种属
兔(Rabbit)
特异性
AHR
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human AHR (AA 724-780)
Recombinant Aryl hydrocarbon Receptor Antibody (Ab089734) - Western Blot All lanes: Recombinant Aryl hydrocarbon Receptor Antibody (Ab089734) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 96 kDa Observed band size: 103 kDa Exposure time: 60 s
Recombinant Aryl hydrocarbon Receptor Antibody (Ab089734) - Western Blot All lanes use Recombinant Aryl hydrocarbon Receptor Antibody (Ab089734) at 1/1000 dilution for 1 hour at room temperature.