Rabbit anti Human BAAT Antibody, Polyclonal, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
规格
产品名称
BAAT Antibody
别名
长链脂肪酸酰基辅酶A水解酶抗体
英文别名
BAAT antibody | BAAT_HUMAN antibody | BACAT antibody | BAT antibody | Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) antibody | Bile acid CoA:amino acid N acyltransferase antibody | Bile acid Coenzyme A amino acid N acyltransfe
规格或纯度
ExactAb™, Validated, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
BAAT
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human BAAT
阳性对照
WB: A549, A431, HeLa, Jurkat and Hep G2 cell lysates.
BAAT Antibody (Ab090441) - Western Blot All lanes: BAAT Antibody (Ab090441) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 46 kDa Observed band size: 41 kDa Exposure time: 5.2 s