ExactAb™,已验证,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
2-8°C储存,禁止冷冻。低温运输,禁止冷冻 。请查阅批次 COA 获取详细规格。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human beta Catenin Antibody, Recombinant (MyR1-CTNNB), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Protein Function
Key dowstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes.
Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
Recombinant beta Catenin Antibody (Ab091082) - IHC
Immunohistochemistry analysis of paraffin-embedded Human appendix tissue labelling beta Catenin with Recombinant beta Catenin Antibody (Ab091082) at 1/100 dilution. The section was incubated with Ab091082 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.
Recombinant beta Catenin Antibody (Ab091082) - IHC
Immunohistochemistry analysis of paraffin-embedded Human appendix tissue labelling beta Catenin with Recombinant beta Catenin Antibody (Ab091082) at 1/100 dilution. The section was incubated with Ab091082 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.
1/100 - 1/200
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0404767 |
分析证书 | Ab091082 |
| ZJ24F0404766 |
分析证书 | Ab091082 |
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