Adenovirus E1B19K-binding protein B5 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like | BCL2/adenovirus E1B 19-kd protein-interacting protein 3a | BCL2/adenovirus E1B 19kDa interac
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. May function as a tumor suppressor. Inhibits apoptosis induced by BNIP3.
宿主种属
兔(Rabbit)
特异性
BNIP3L
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
预测反应种属
牛(Cow)
免疫原
A synthetic peptide derived from human BNIP3L/NIX (AA 150-219)
阳性对照
WB: HeLa, MCF7, K562 and NIH/3T3 cell lysates. IF/ICC: HeLa cells.
Recombinant BNIP3L/NIX Antibody (Ab091477) - Western Blot All lanes: Recombinant BNIP3L/NIX Antibody (Ab091477) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution
Predicted band size: 24 kDa Observed band size: 32-39, 64 kDa BNIP3L forms homodimers that withstand denaturing by SDS and reducing conditions (PMID: 10467396). Exposure time: 30.7 s
Recombinant BNIP3L/NIX Antibody (Ab091477) - IF/ICC Immunofluorescent analysis of HeLa cells, using Recombinant BNIP3L/NIX Antibody (Ab091477) at 1/50 dilution.
ZJ25F0116416
危险品化学品经营许可证（带存储）