Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
宿主种属
兔(Rabbit)
特异性
CNR1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse),猴(Monkey)
免疫原
A synthetic peptide derived from human Cannabinoid Receptor I (AA 151-200).
阳性对照
WB: Rat brain, HT-29 lysates. IHC: Human brain tissue. IF/ICC: LOVO cells.
Cannabinoid Receptor I Antibody (Ab092707) - Western Blot All lanes: Cannabinoid Receptor I Antibody (Ab092707) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 53 kDa Observed band size: 49 kDa Exposure time: 130.0 s
Cannabinoid Receptor I Antibody (Ab092707) - Western Blot All lanes: Cannabinoid Receptor I Antibody (Ab092707) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 53 kDa Observed band size: 49 kDa Exposure time: 130.0 s
Cannabinoid Receptor I Antibody (Ab092707) - IHC Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Cannabinoid Receptor I Antibody (Ab092707). The picture on the right is blocked with the synthesized peptide.
Cannabinoid Receptor I Antibody (Ab092707) - IF/ICC Immunofluorescence analysis of LOVO cells, using Cannabinoid Receptor I Antibody (Ab092707). The picture on the right is blocked with the synthesized peptide.