Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp- -Gly-217' bond. Overexpression promotes programmed cell death.
宿主种属
兔(Rabbit)
特异性
Caspase-7
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human Caspase-7 (AA 1-42).
阳性对照
WB: Jurkat, HeLa, Hep G2, MCF7 and MOLT-4 cell lysates.
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Caspase-7 Antibody (Ab093046) - Western Blot All lanes: Recombinant Caspase-7 Antibody (Ab093046) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 34 kDa Observed band size: 33 kDa Exposure time: 122.3 s